BIOMOLECULAS
BIOMOLECULAS
Publications (27) Publications in which a researcher has participated View referenced research data.
2025
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Stable and Promiscuous Galactose Oxidases Engineered by Directed Evolution, Atomistic Design, and Ancestral Sequence Reconstruction
ACS Synthetic Biology, Vol. 14, Núm. 1, pp. 239-246
2022
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Active site center redesign increases protein stability preserving catalysis in thioredoxin
Protein Science, Vol. 31, Núm. 9
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Efficient Base-Catalyzed Kemp Elimination in an Engineered Ancestral Enzyme
International journal of molecular sciences, Vol. 23, Núm. 16
2021
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Combining Ancestral Reconstruction with Folding-Landscape Simulations to Engineer Heterologous Protein Expression: Engineering heterologous protein expression
Journal of Molecular Biology, Vol. 433, Núm. 24
2020
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A quantitative assay to study the lipid selectivity of membrane-associated systems using solution NMR
Chemical Communications, Vol. 56, Núm. 78, pp. 11665-11668
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Ancestral resurrection and directed evolution of fungal mesozoic laccases
Applied and Environmental Microbiology, Vol. 86, Núm. 14
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Consensus Design of an Evolved High-Redox Potential Laccase
Frontiers in Bioengineering and Biotechnology, Vol. 8
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Enhancing a: De novo enzyme activity by computationally-focused ultra-low-throughput screening
Chemical Science, Vol. 11, Núm. 24, pp. 6134-6148
2019
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Anion-specific interaction with human NQO1 inhibits flavin binding
International Journal of Biological Macromolecules, Vol. 126, pp. 1223-1233
2018
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Biotechnological and protein-engineering implications of ancestral protein resurrection
Current Opinion in Structural Biology, Vol. 51, pp. 106-115
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Directed -in vitro- Evolution of precambrian and extant rubiscos
Scientific Reports, Vol. 8, Núm. 1
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Improving the Activity and Stability of Human Galactokinase for Therapeutic and Biotechnological Applications
ChemBioChem, Vol. 19, Núm. 10, pp. 1088-1095
2016
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Engineering ancestral protein hyperstability
Biochemical Journal, Vol. 473, Núm. 20, pp. 3611-3620
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Oligomeric status of human cystathionine beta-synthase modulates AdoMet binding
FEBS Letters, Vol. 590, Núm. 24, pp. 4461-4471
2015
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Biochemical and Mutational Characterization of N-Succinyl-Amino Acid Racemase from Geobacillus stearothermophilus CECT49
Molecular Biotechnology, Vol. 57, Núm. 5, pp. 454-465
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Enzymatic dynamic kinetic resolution of racemic N-formyl- and N-carbamoyl-amino acids using immobilized l-N-carbamoylase and N-succinyl-amino acid racemase
Applied Microbiology and Biotechnology, Vol. 99, Núm. 1, pp. 283-291
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McCLEC, a robust and stable enzymatic based microreactor platform
Lab on a Chip, Vol. 15, Núm. 20, pp. 4083-4089
2013
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Mechanism of Protein Kinetic Stabilization by Engineered Disulfide Crosslinks
PLoS ONE, Vol. 8, Núm. 7
2011
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Single-molecule paleoenzymology probes the chemistry of resurrected enzymes
Nature Structural and Molecular Biology, Vol. 18, Núm. 5, pp. 592-596
2010
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Protein kinetic stability
Biophysical Chemistry, Vol. 148, Núm. 1-3, pp. 1-15