Publications (18) Publications in which a researcher has participated View referenced research data.

filter_list Genetics

2021

  1. Combining Ancestral Reconstruction with Folding-Landscape Simulations to Engineer Heterologous Protein Expression: Engineering heterologous protein expression

    Journal of Molecular Biology, Vol. 433, Núm. 24

2019

  1. Insight into the specificity and severity of pathogenic mechanisms associated with missense mutations through experimental and structural perturbation analyses

    Human Molecular Genetics, Vol. 28, Núm. 1, pp. 1-15

  2. Non-conservation of folding rates in the thioredoxin family reveals degradation of ancestral unassisted-folding

    Biochemical Journal, Vol. 476, Núm. 23, pp. 3631-3647

  3. Phosphorylation compromises FAD binding and intracellular stability of wild-type and cancer-associated NQO1: Insights into flavo-proteome stability

    International Journal of Biological Macromolecules, Vol. 125, pp. 1275-1288

2018

  1. Conformational dynamics and enzyme evolution

    Journal of the Royal Society Interface, Vol. 15, Núm. 144

  2. Directed -in vitro- Evolution of precambrian and extant rubiscos

    Scientific Reports, Vol. 8, Núm. 1

  3. Natural (and Unnatural) Small Molecules as Pharmacological Chaperones and Inhibitors in Cancer

    Handbook of Experimental Pharmacology (Springer New York LLC), pp. 155-190

2017

  1. De novo active sites for resurrected Precambrian enzymes

    Nature Communications, Vol. 8

2015

  1. Mutational studies on resurrected ancestral proteins reveal conservation of site-specific amino acid preferences throughout evolutionary history

    Molecular Biology and Evolution, Vol. 32, Núm. 2, pp. 440-455

2014

  1. The lower limits for protein stability and foldability in primary hyperoxaluria type i

    Biochimica et Biophysica Acta - Proteins and Proteomics, Vol. 1844, Núm. 12, pp. 2355-2365

2013

  1. The Role of Protein Denaturation Energetics and Molecular Chaperones in the Aggregation and Mistargeting of Mutants Causing Primary Hyperoxaluria Type I

    PLoS ONE, Vol. 8, Núm. 8

2012

  1. Probing the mutational interplay between primary and promiscuous protein functions: A computational-experimental approach

    PLoS Computational Biology, Vol. 8, Núm. 6

2011

  1. Highly anomalous energetics of protein cold denaturation linked to Folding-Unfolding kinetics

    PLoS ONE, Vol. 6, Núm. 7

  2. Role of low native state kinetic stability and interaction of partially unfolded states with molecular chaperones in the mitochondrial protein mistargeting associated with primary hyperoxaluria

    Amino Acids, Vol. 41, Núm. 5, pp. 1233-1245

2010

  1. Navigating the downhill protein folding regime via structural homologues

    Journal of the American Chemical Society, Vol. 132, Núm. 32, pp. 11183-11190

2009

  1. Thermodynamic and Kinetic Characterization of a Germ Line Human λ6 Light-Chain Protein: The Relation between Unfolding and Fibrillogenesis

    Journal of Molecular Biology, Vol. 386, Núm. 4, pp. 1153-1166

2006

  1. A simple tool to explore the distance distribution of correlated mutations in proteins

    Biophysical Chemistry, Vol. 119, Núm. 3, pp. 240-246

2004

  1. Relation Between Protein Stability, Evolution and Structure, as Probed by Carboxylic Acid Mutations

    Journal of Molecular Biology, Vol. 336, Núm. 2, pp. 313-318