Publications (8) Publications in which a researcher has participated View referenced research data.

filter_list Internal Medicine

2019

  1. NAD(P)H quinone oxidoreductase (NQO1): An enzyme which needs just enough mobility, in just the right places

    Bioscience Reports, Vol. 39, Núm. 1

  2. NQO1: A target for the treatment of cancer and neurological diseases, and a model to understand loss of function disease mechanisms

    Biochimica et Biophysica Acta - Proteins and Proteomics, Vol. 1867, Núm. 7-8, pp. 663-676

2018

  1. Biophysical and functional perturbation analyses at cancer-associated P187 and K240 sites of the multifunctional NADP(H):quinone oxidoreductase 1

    International Journal of Biological Macromolecules, Vol. 118, pp. 1912-1923

2017

  1. A mechanism for cancer-associated inactivation of NQO1 due to P187S and its reactivation by the consensus mutation H80R

    FEBS Letters, Vol. 591, Núm. 18, pp. 2826-2835

  2. Site-to-site interdomain communication may mediate different loss-of-function mechanisms in a cancer-associated NQO1 polymorphism

    Scientific Reports, Vol. 7

2016

  1. Natural small molecules as stabilizers and activators of cancer-associated NQO1 polymorphisms

    Current Drug Targets, Vol. 17, Núm. 13, pp. 1506-1514

2015

  1. Evolution of Conformational Dynamics Determines the Conversion of a Promiscuous Generalist into a Specialist Enzyme

    Molecular Biology and Evolution, Vol. 32, Núm. 1, pp. 132-143

2014

  1. FAD binding overcomes defects in activity and stability displayed by cancer-associated variants of human NQO1

    Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1842, Núm. 11, pp. 2163-2173