Publications (11) Publications in which a researcher has participated View referenced research data.

filter_list Pharmacology

2023

  1. Structure-based discovery and in vitro validation of inhibitors of chloride intracellular channel 4 protein

    Computational and Structural Biotechnology Journal, Vol. 21, pp. 688-701

2019

  1. Equilibrium partially folded states of B. licheniformis β-lactamase

    European Biophysics Journal, Vol. 48, Núm. 4, pp. 341-348

  2. Synthesis and biological evaluation of new long-chain squaramides as anti-chagasic agents in the BALB/c mouse model

    Bioorganic and Medicinal Chemistry, Vol. 27, Núm. 5, pp. 865-879

  3. Warfarin increases thermal resistance of albumin through stabilization of the protein lobe that includes its binding site

    Archives of Biochemistry and Biophysics, Vol. 676

2018

  1. Second Generation of Mannich Base-Type Derivatives with in Vivo Activity against Trypanosoma cruzi

    Journal of Medicinal Chemistry, Vol. 61, Núm. 13, pp. 5643-5663

  2. Synthesis and Biological in vitro and in vivo Evaluation of 2-(5-Nitroindazol-1-yl)ethylamines and Related Compounds as Potential Therapeutic Alternatives for Chagas Disease

    ChemMedChem, Vol. 13, Núm. 19, pp. 2104-2118

2015

  1. Evolution of Conformational Dynamics Determines the Conversion of a Promiscuous Generalist into a Specialist Enzyme

    Molecular Biology and Evolution, Vol. 32, Núm. 1, pp. 132-143

2014

  1. Phenotypic comparisons of consensus variants versus laboratory resurrections of Precambrian proteins

    Proteins: Structure, Function and Bioinformatics, Vol. 82, Núm. 6, pp. 887-896

2013

  1. Hyperstability and substrate promiscuity in laboratory resurrections of precambrian β-lactamases

    Journal of the American Chemical Society, Vol. 135, Núm. 8, pp. 2899-2902

  2. Protein homeostasis defects of alanine-glyoxylate aminotransferase: New therapeutic strategies in primary hyperoxaluria type i

    BioMed Research International, Vol. 2013

2002

  1. Electrostatic interactions in ubiquitin: Stabilization of carboxylates by lysine amino groups

    Biochemistry, Vol. 41, Núm. 24, pp. 7586-7596