Publications (14) Publications in which a researcher has participated

filter_list Organic Chemistry

2025

  1. Development of selective sigma-1 receptor ligands with antiallodynic activity: A focus on piperidine and piperazine scaffolds

    European Journal of Medicinal Chemistry, Vol. 281

2023

  1. Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity

    Journal of Medicinal Chemistry, Vol. 66, Núm. 16, pp. 11447-11463

  2. Synthesis, Computational Insights, and Evaluation of Novel Sigma Receptors Ligands

    ACS Chemical Neuroscience, Vol. 14, Núm. 10, pp. 1845-1858

2022

  1. Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H3 and Sigma-1 Receptor Antagonists with Promising Antinociceptive Properties

    ACS Chemical Neuroscience, Vol. 13, Núm. 1, pp. 1-15

  2. Synthesis of tropane-based σ1 receptor antagonists with antiallodynic activity

    European Journal of Medicinal Chemistry, Vol. 230

2021

  1. Chemoenzymatic synthesis of 2,6-disubstituted tetrahydropyrans with high σ1 receptor affinity, antitumor and analgesic activity

    European Journal of Medicinal Chemistry, Vol. 219

  2. Tricyclic Triazoles as σ1Receptor Antagonists for Treating Pain

    Journal of Medicinal Chemistry, Vol. 64, Núm. 8, pp. 5157-5170

2020

  1. Novel N-Substituted Benzomorphan-Based Compounds: From MOR-Agonist/DOR-Antagonist to Biased/Unbiased MOR Agonists

    ACS Medicinal Chemistry Letters, Vol. 11, Núm. 5, pp. 678-685

2019

  1. Tetrahydro-3-benzazepines with fluorinated side chains as NMDA and σ1 receptor antagonists: Synthesis, receptor affinity, selectivity and antiallodynic activity

    European Journal of Medicinal Chemistry, Vol. 177, pp. 47-62

2018

  1. (+)-Methyl (1 R, 2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] derivatives as potent and selective sigma receptor ligands: Stereochemistry and pharmacological properties

    Journal of Medicinal Chemistry, Vol. 61, Núm. 1, pp. 372-384

  2. Synthesis, Receptor Affinity, and Antiallodynic Activity of Spirocyclic σ Receptor Ligands with Exocyclic Amino Moiety

    Journal of Medicinal Chemistry, Vol. 61, Núm. 21, pp. 9666-9690

2017

  1. (+)-and (−)-Phenazocine enantiomers: Evaluation of their dual opioid agonist/σ1antagonist properties and antinociceptive effects

    European Journal of Medicinal Chemistry, Vol. 125, pp. 603-610

2013

  1. Antiallodynic and analgesic effects of maslinic acid, a pentacyclic triterpenoid from Olea europaea

    Journal of Natural Products, Vol. 76, Núm. 4, pp. 737-740

2011

  1. Novel potent and selective θ ligands: Evaluation of their agonist and antagonist properties

    Journal of Medicinal Chemistry, Vol. 54, Núm. 10, pp. 3669-3673