
JOSÉ ANTONIO
GAVIRA GALLARDO
Publications (18) JOSÉ ANTONIO GAVIRA GALLARDO publications
2023
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First 3-D structural evidence of a native-like intertwined dimer in the acylphosphatase family
Biochemical and Biophysical Research Communications, Vol. 682, pp. 85-90
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Protection of Catalytic Cofactors by Polypeptides as a Driver for the Emergence of Primordial Enzymes
Molecular Biology and Evolution, Vol. 40, Núm. 6
2022
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Structural insights into choline-O-sulfatase reveal the molecular determinants for ligand binding
Acta crystallographica. Section D, Structural biology, Vol. 78, pp. 669-682
2021
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Combining Ancestral Reconstruction with Folding-Landscape Simulations to Engineer Heterologous Protein Expression: Engineering heterologous protein expression
Journal of Molecular Biology, Vol. 433, Núm. 24
2020
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Enhancing a: De novo enzyme activity by computationally-focused ultra-low-throughput screening
Chemical Science, Vol. 11, Núm. 24, pp. 6134-6148
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Evidence for pentapeptide-dependent and independent cheb methylesterases
International Journal of Molecular Sciences, Vol. 21, Núm. 22, pp. 1-20
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How bacterial chemoreceptors evolve novel ligand specificities
mBio, Vol. 11, Núm. 1
2019
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Non-conservation of folding rates in the thioredoxin family reveals degradation of ancestral unassisted-folding
Biochemical Journal, Vol. 476, Núm. 23, pp. 3631-3647
2018
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Functional annotation of bacterial signal transduction systems: Progress and challenges
International Journal of Molecular Sciences, Vol. 19, Núm. 12
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High-affinity chemotaxis to histamine mediated by the TlpQ chemoreceptor of the human pathogen pseudomonas aeruginosa
mBio, Vol. 9, Núm. 6
2015
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Mutational studies on resurrected ancestral proteins reveal conservation of site-specific amino acid preferences throughout evolutionary history
Molecular Biology and Evolution, Vol. 32, Núm. 2, pp. 440-455
2013
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Purification, crystallization and preliminary crystallographic analysis of the ligand-binding regions of the PctA and PctB chemoreceptors from Pseudomonas aeruginosa in complex with amino acids
Acta Crystallographica Section F: Structural Biology and Crystallization Communications, Vol. 69, Núm. 12, pp. 1431-1435
2012
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Evidence for chemoreceptors with bimodular ligand-binding regions harboring two signal-binding sites
Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Núm. 46, pp. 18926-18931
2010
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Novel conformational aspects of the third PDZ domain of the neuronal post-synaptic density-95 protein revealed from two 1.4Å X-ray structures
Journal of Structural Biology, Vol. 170, Núm. 3, pp. 565-569
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Structure of dihydropyrimidinase from Sinorhizobium meliloti CECT4114: New features in an amidohydrolase family member
Journal of Structural Biology, Vol. 169, Núm. 2, pp. 200-208
2008
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Force-clamp spectroscopy detects residue co-evolution in enzyme catalysis
Journal of Biological Chemistry, Vol. 283, Núm. 40, pp. 27121-27129
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Structure and ligand selection of hemoglobin II from Lucina pectinata
Journal of Biological Chemistry, Vol. 283, Núm. 14, pp. 9414-9423
2005
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Life in the fast lane for protein crystallization and X-ray crystallography
Progress in Biophysics and Molecular Biology, Vol. 88, Núm. 3, pp. 359-386