Determinación de la estabilidad de Kollicoat MAE 30D mediante medidas de calorimetría diferencial de barrido

  1. Ruiz, Mª A. 1
  2. López Viota, M. 1
  3. Arias, JL. 1
  4. Gallardo, V. 1
  1. 1 Universidad de Granada
    info

    Universidad de Granada

    Granada, España

    ROR https://ror.org/04njjy449

Revista:
Ars pharmaceutica

ISSN: 2340-9894,  0004-2927

Ano de publicación: 2008

Volume: 49

Número: 1

Páxinas: 67-76

Tipo: Artigo

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Outras publicacións en: Ars pharmaceutica

Resumo

The stability of Kollicoat MAE 30 D was studied with differential scanning calorimetric, and scanning electron microscopy. We investigated the effects of pH, temperature and shaking on physicochemical properties of the latex particles. Stability of the polymer as most strongly affected by pH; hence, we conclude that the stability of this latex reaches a maximum at acid pH values, where as stability is lost to pH 6. The particle shape and the mean diameter were determined by means of SEM microphotographs on 200 particles in a sample of dry latex. The aqueous Kollicoat MAE 30 D dispersion, at its natural pH (2.5), presented one population of particles with a mean diameter of 1.56 nm.

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