Neurogénesis hipocampal adulta y envejecimiento cognitivo

  1. Román Darío Moreno Fernández
  2. Carmen Pedraza
  3. Milagros Gallo
Revista:
Escritos de psicología

ISSN: 1138-2635 1989-3809

Año de publicación: 2013

Volumen: 6

Número: 3

Páginas: 14-24

Tipo: Artículo

DOI: 10.5231/PSY.WRIT.2013.2510 DIALNET GOOGLE SCHOLAR lock_openDialnet editor

Otras publicaciones en: Escritos de psicología

Resumen

El envejecimiento es un proceso normal en el desarrollo del organismo asociado a una serie de cambios neurobiológicos que producen alteraciones cognitivas con funciones preservadas, deterioradas y facilitadas. Se revisa la evidencia obtenida con animales y humanos a fin de explorar un posible papel de la plasticidad hipocampal en los cambios cognitivos asociados con la edad, con especial atención a la neurogénesis hipocampal adulta. Los resultados obtenidos empleando las estrategias de lesión, estimulación, así como datos correlacionales apoyan un papel, ya sea directo, ya sea modulador de las nuevas neuronas en la ejecución cognitiva a edades avanzadas. Avances en la investigación de esta relación pueden favorecer el desarrollo de nuevos tratamientos y la mejora de la calidad de vida de la población de más edad.

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