Cortical contrast processing in retinitis pigmentosaevidence of PVEPs spatial functions

  1. Rafael Mancebo-Azor 1
  2. José Antonio Sáez-Moreno 2
  3. José Manuel Rodríguez-Ferrer 3
  1. 1 Laboratory of Visual and Cognitive Neuroscience, Institute of Neuroscience, University of Granada
  2. 2 Department of Clinical Neurophysiology, San Cecilio University Hospital
  3. 3 Department of Physiology, University of Granada
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Revue:
EJIHPE: European Journal of Investigation in Health, Psychology and Education

ISSN: 2174-8144,  2254-9625

Année de publication: 2020

Titre de la publication: Sociodemographic characteristics and stress of people from Spain confined by COVID-19

Volumen: 10

Número: 4

Pages: 1010-1019

Type: Article

DOI: 10.3390/EJIHPE10040071 DIALNET GOOGLE SCHOLAR lock_openDialnet editor

D'autres publications dans: EJIHPE: European Journal of Investigation in Health, Psychology and Education

Résumé

Objective: To study the effect of check width size of the stimuli on the amplitude and latency of the P100 component of visual evoked potentials recorded in patients with retinitis pigmentosa (RP). Methods: Pattern reversal visual evoked potentials (PVEPs) were recorded in 16 RP patients and 20 visually normal subjects. Pattern reversal stimuli with five different check widths and 100% of contrast were projected in the right eye of both patients and control subjects. PVEPs induced by stimuli with 78%, 16%, and 6% of contrast were also recorded in 10 of the control subjects. Results: In RP patients, the amplitude of P100 was smaller than controls in all check sized used and the peak P100 amplitude was obtained with a larger check width than in controls. P100 was also delayed in RP patients in all check sizes studied. The P100 amplitude- and latency-check size functions of RP patients were like those found in control subjects with low contrast stimuli of 16% and 6%. Conclusion: The PVEPs spatial functions of RP patients show quantitative and qualitative changes, suggesting disease induced alteration in the neural processing of stimulus contrast.

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This research was funded by the Junta de Andalucía. Project PB98-1311

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