Caracterización y estudio de solubilidad de mezclas binarias de flurarizina polietilenglicol 4000

  1. Marín Boscá, Mª T.
  2. Margarit Bellver, Mª V.
  3. Martín Ramos, JD
Revista:
Ars pharmaceutica

ISSN: 2340-9894 0004-2927

Año de publicación: 2002

Volumen: 43

Número: 1-2

Páginas: 73-82

Tipo: Artículo

Otras publicaciones en: Ars pharmaceutica

Referencias bibliográficas

  • Andersson K -E, Vinge E. β-Adrenoceptor blockers and calcium antagonists in the prophylaxis and treatment of migraine. Drugs 1990; 39: 355-373.
  • Olesen J. A review of current drugs for migraine. J. Neurol. 1991; 238: S23-S27.
  • Holmes B, Brogden R N, Heel R C, Speight T M, Avery G S. Flunarizine: A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use. Drugs 1984; 7: 6-44.
  • Marini D, Balestrieri F. Flunarizine. Caratterizzazione chimica e chimico-fisica. Boll.Chim. Farm. 1984; 123: 133-140.
  • Sekiguchi K, Obi N. Studies of absorption of eutectic mixture. I. A comparison of the behavior of eutectic mixture of sulfathiazole and that of ordinary sulfathiazole in man. Chem. Pharm. Bull. 1961; 9: 866–872.
  • Chiou W L, Riegelman S. Pharmaceutical applications of solid dispersion systems. J. Pharm. Sci. 1971; 6: 1281-1303.
  • Ford J L. The current status of solid dispersions. Pharm. Acta Helv. 1986; 61: 69-88.
  • Margarit M V, Rodríguez I C, Cerezo A. Physical characteristics and dissolution kinetics of solid dispersions of ketoprofen and polyethylene glycol 6000. Int. J. Pharm. 1994; 108: 101-107.
  • Margarit M V, Marín M T, Contreras M D. Solubility of solid dispersions of pizotifen malate and povidone. Drug Dev. & Ind. Pharm. 2001; 27: 517-522.
  • Mura P, Faucci M T, Manderioli A, Bramanti G, Parrini P. Thermal behavior and dissolution properties of naproxen from binary and ternary solid dispersions. Drug Dev. Ind. Pharm. 1999; 25: 257-264.
  • El-Gazayerly O N. Characterization and evaluation of tenoxicam coprecipitates. Drug Dev. & Ind. Pharm. 2000; 26: 925-930.
  • Iannuccelli V, Coppi G, Leo E, Fontana F, Bernabei M T. Poly- vinylpyrrolidone solid dispersions for the controlled release of furosemide from a floating multiple-unit system. Drug Dev. & Ind. Pharm. 2000; 26: 595-603.
  • Craig D Q M. Polyethylene glycols and drug release. Drug Dev. & Ind. Pharm. 1990; 16: 2501-2526.
  • Arias M J, Ginés J M, Moyano J R, Perez-Barrales M J, Vela M T, Rabasco A M. Improvement of the diuretic effect of triamterene via solid dispersion technique with PEG 4000. Eur. J. Drug Metab. Pharmacokinet. 1994; 4: 295-302.
  • Trapani G, Franco M, Latrofa A, Pantaleo M R, Provenzano M R, Sanna E et al. Physicochemical characterization and in vivo properties of zolpidem in solid dispersions with polyethylene glycol 4000 and 6000. Int. J. Pharm. 1999; 184: 121-130.
  • Lloyd G R, Craig D Q M, Smith A. A calorimetric investigation into the interaction between paracetamol and polyethylene glycol 4000 in physical mixes and solid dispersions. Eur. J. Pharm. and Biopharm. 1999; 48: 59-65.
  • Martín J D (1996) Programa para la obtención e interpretación de diagramas de difracción de rayos X por el método de polvo. Depto. de Mineralogía y Petrología. Fac. de Ciencias. Univ. de Granada, España.
  • Dordunno S K, Ford J L, Rubinstein M H. Preformulaton studies on solid dispersions containing triamterene or temazepam in polyethylene glycols or gelucire 44/14 for liquid filling of hard gelatin capsules. Drug Dev. & Ind. Pharm. 1991; 17: 1685-1713.
  • Arias M J, Moyano J R, Gines J M. (1998).Study by DSC of the oxacepam-PEG 6000 and oxazepam-D-manitol systems: Application to the preparation of solid dispersions. Thermochimica Acta. 1998; 321: 33–41.