Transformación de Neoplasia Intraepitelial Conjuntival a Carcinoma de Células Escamosas Conjuntival a pesar de tratamiento tópico con Interferon α2b

  1. Ortega-Molina, JM
  2. Solans Pérez-Larraya, AM
  3. Retamero, JA
  4. Contreras-Medrano, MA
  5. Gascón-Ginel, I
Revue:
Actualidad médica

ISSN: 0365-7965

Année de publication: 2016

Tomo: 101

Número: 799

Pages: 193-195

Type: Article

DOI: 10.15568/AM.2016.799.CC03 DIALNET GOOGLE SCHOLAR lock_openDIGIBUG editor

D'autres publications dans: Actualidad médica

Objectifs de Développement Durable

Résumé

Clinical case: A 69 year old woman presented with a conjunctival mass in her right eye (OD) for the previous 3 months. It was observed a mass of 3x8mm involving the nasal conjunctiva. Citolology study was performed showing a conjunctival intraepithelial neoplasia (NIC). Initially the lesion decreased in size (2x5mm) after topical interferon α2b (IFN-α2b) 1 MUI/ml treatment was prescribed. However, 6 months later, a new growth of the NIC was observed, so we decided surgical treatment. Histopathological study confirmed the diagnosis of conjunctival squamous cell carcinoma (SCC). Conclusions : Treatment with IFN-α2b is being preferred to surgical excision for NIC, due to its good results obtained, low recurrence and its few adverse effects. However, ineffective cases and progression to SCC of conjunctiva have been reported.

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