Estatinas:Características y Efectos sobre el Control Lipídico en el Niño y Adolescente Obeso

  1. E. González Jiménez 1
  2. J. Álvarez Ferre 2
  1. 1 Departamento de Enfermería. Facultad de Ciencias de la Salud. Universidad de Granada. Granada (España)
  2. 2 Unidad de Hospitalización Crónica. Hospital Universitario San Rafael. Granada (España)
Revista:
Revista Clínica de Medicina de Familia

ISSN: 2386-8201

Año de publicación: 2011

Volumen: 4

Número: 1

Páginas: 69-75

Tipo: Artículo

Otras publicaciones en: Revista Clínica de Medicina de Familia

Resumen

La obesidad en niños y adolescentes representa un problema emergente de salud pública, siendo el trastorno nutricional y metabólico más prevalente en los países desarrollados. Paralelo a este incremento de obesidad, han hecho su aparición dislipemias a edades cada vez más tempranas. En la última década se han producido novedosos avances en el tratamiento de estas alteraciones lipídicas, fundamentalmente debido a la introducción de las estatinas en su terapia. Su utilidad y eficacia ampliamente demostrada en adultos parece ser igualmente aplicable en el tratamiento de las hipercolesterolemias durante la infancia. En la actualidad son seis ya las estatinas utilizadas en población infantil, habiendo sido analizada su actividad en niños y jóvenes a través de ensayos clínicos, en los que se concluye su eficacia y seguridad para reducir las concentraciones tanto de colesterol total como de colesterol en lipoproteínas de baja densidad (c-LDL) en sangre. El objetivo de este trabajo ha sido ofrecer una revisión actualizada sobre las características de éstas y sus efectos en la mejora clínica de los niveles de lípidos en sangre en niños y adolescentes con sobrepeso y obesidad.

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