Additional file 2 of Cortistatin deficiency reveals a dysfunctional brain endothelium with impaired gene pathways, exacerbated immune activation, and disrupted barrier integrity

  1. Castillo-González, Julia 1
  2. Ruiz, José Luis 1
  3. Serrano-Martínez, Ignacio 1
  4. Forte-Lago, Irene 1
  5. Ubago-Rodriguez, Ana 1
  6. Caro, Marta 1
  7. Pérez-Gómez, Jesús Miguel 234
  8. Benítez-Troncoso, Alejandro 1
  9. Andrés-León, Eduardo 1
  10. Sánchez-Navarro, Macarena 1
  11. Luque, Raúl M. 234
  12. González-Rey, Elena 1
  1. 1 Instituto de Parasitología y Biomedicina López Neyra
    info

    Instituto de Parasitología y Biomedicina López Neyra

    Armilla, España

    ROR https://ror.org/05ncvzk72

  2. 2 Hospital Universitario Reina Sofia
    info

    Hospital Universitario Reina Sofia

    Córdoba, España

    ROR https://ror.org/02vtd2q19

  3. 3 Universidad de Córdoba
    info

    Universidad de Córdoba

    Córdoba, España

    ROR https://ror.org/05yc77b46

  4. 4 Instituto Maimónides de Investigación Biomédica de Córdoba
    info

    Instituto Maimónides de Investigación Biomédica de Córdoba

    Córdoba, España

    ROR https://ror.org/00j9b6f88

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Editor: figshare

Ano de publicación: 2024

Tipo: Dataset

CC BY 4.0

DOI: 10.6084/M9.FIGSHARE.26622787 lock_openAcceso aberto editor

Resumo

Additional file 2: Table S3. Differentially expressed genes (DEGs) in Cort−/−  BECs in NX/NG compared to Cort+/+ BECs. Table S4. Differentially expressed genes (DEGs) in Cort−/− BECs in OGD-R compared to Cort+/+ BECs. Table S5. DEGs for NX/NG-incubated Cort−/− vs Cort+/+ BECs included in Gene Ontology (GO) terms. Table S6. DEGs for OGD-R-incubated Cort−/− vs Cort+/+ BECs included in Gene Ontology (GO) terms. Table S7. Differentially expressed genes (DEGs) in the dynamics of Cort+/+ BECs from NX/NG to OGD-R. Table S8. Differentially expressed genes (DEGs) in the dynamics of Cort−/− BECs from NX/NG to OGD-R. Table S9. DEGs for Cort+/+ BECs from NX/NG to OGD-R included in Gene Ontology (GO) terms. Table S10. DEGs for Cort−/− BECs from NX/NG to OGD-R included in Gene Ontology (GO) terms. Table S11. Comparative values between log2FC and RPKM for differentially expressed genes (DEGs) depicted in Fig. 7.

Referencias bibliográficas

  • 10.1007/978-1-4939-0320-7_28
  • 10.1101/2023.07.12.548663
  • 10.3389/fneur.2020.563916
  • 10.1007/164_2020_404