Publications in collaboration with researchers from Institut d'Investigació Biomèdica Girona (31)

2022

  1. Silibinin Overcomes EMT-Driven Lung Cancer Resistance to New-Generation ALK Inhibitors

    Cancers, Vol. 14, Núm. 24

2020

  1. Mimetics of extra virgin olive oil phenols with anti-cancer stem cell activity

    Aging, Vol. 12, Núm. 21, pp. 21057-21075

2019

  1. An olive oil phenolic is a new chemotype of mutant isocitrate dehydrogenase 1 (IDH1) inhibitors

    Carcinogenesis, Vol. 40, Núm. 1, pp. 27-40

  2. Computational de-orphanization of the olive oil biophenol oleacein: Discovery of new metabolic and epigenetic targets

    Food and Chemical Toxicology, Vol. 131

  3. The extra virgin olive oil phenolic oleacein is a dual substrate-inhibitor of catechol-O-methyltransferase

    Food and Chemical Toxicology, Vol. 128, pp. 35-45

2018

  1. A phase 2 trial of neoadjuvant metformin in combination with trastuzumab and chemotherapy in women with early HER2-positive breast cancer: The METTEN study

    Oncotarget, Vol. 9, Núm. 86, pp. 35687-35704

  2. Extra-virgin olive oil contains a metabolo-epigenetic inhibitor of cancer stem cells

    Carcinogenesis, Vol. 39, Núm. 4, pp. 601-613

2016

  1. Exploring the Process of Energy Generation in Pathophysiology by Targeted Metabolomics: Performance of a Simple and Quantitative Method

    Journal of the American Society for Mass Spectrometry, Vol. 27, Núm. 1, pp. 168-177

2015

  1. Proanthocyanidins in agro-industrial by-products: Health benefits

    Occurrences, Structure, Biosynthesis, and Health Benefits Based on Their Evidences of Medicinal Phytochemicals in Vegetables and Fruits. Volume 3 (Nova Science Publishers, Inc.), pp. 63-114

2014

  1. Computer-aided discovery of biological activity spectra for anti-aging and anti-cancer olive oil oleuropeins

    Aging, Vol. 6, Núm. 9, pp. 731-741

  2. Oncobiguanides: Paracelsus' law and nonconventional routes for administering diabetobiguanides for cancer treatment

    Oncotarget, Vol. 5, Núm. 9, pp. 2344-2348

2013

  1. Dietary restriction-resistant human tumors harboring the PIK3CA-activating mutation H1047R are sensitive to metformin

    Oncotarget, Vol. 4, Núm. 9, pp. 1484-1495

  2. Multifunctional targets of dietary polyphenols in disease: A case for the chemokine network and energy metabolism

    Food and Chemical Toxicology, Vol. 51, Núm. 1, pp. 267-279

  3. Silibinin meglumine, a water-soluble form of milk thistle silymarin, is an orally active anti-cancer agent that impedes the epithelial-to-mesenchymal transition (EMT) in EGFR-mutant non-small-cell lung carcinoma cells

    Food and Chemical Toxicology, Vol. 60, pp. 360-368

  4. Silibinin suppresses EMT-driven erlotinib resistance by reversing the high miR-21/low miR-200c signature in vivo

    Scientific Reports, Vol. 3

  5. Stem cell-like ALDHbright cellular states in EGFR-mutant non-small cell lung cancer a novel mechanism of acquired resistance to erlotinib targetable with the natural polyphenol silibinin

    Cell Cycle, Vol. 12, Núm. 21, pp. 3390-3404

  6. Xenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil: A new family of gerosuppressant agents

    Cell Cycle, Vol. 12, Núm. 4, pp. 555-578

2012

  1. Metabolomic fingerprint reveals that metformin impairs one-carbon metabolism in a manner similar to the antifolate class of chemotherapy drugs

    Aging, Vol. 4, Núm. 7, pp. 480-498

  2. Metformin lowers the threshold for stress-induced senescence: A role for the microRNA-200 family and miR-205

    Cell Cycle, Vol. 11, Núm. 6, pp. 1235-1246

  3. Phenolic secoiridoids in extra virgin olive oil impede fibrogenic and oncogenic epithelial-to-mesenchymal transition: Extra virgin olive oil as a source of novel antiaging phytochemicals

    Rejuvenation Research, Vol. 15, Núm. 1, pp. 3-21