GENOMICA FUNCIONAL Y EVOLUTIVA
GENETICA DE MAMIFEROS
Wellcome Trust Sanger Institute
Cambridge, Reino UnidoPublicaciones en colaboración con investigadores/as de Wellcome Trust Sanger Institute (12)
2022
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Immune disease risk variants regulate gene expression dynamics during CD4+ T cell activation
Nature Genetics, Vol. 54, Núm. 6, pp. 817-826
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Immune disease variants modulate gene expression in regulatory CD4+ T cells
Cell Genomics, Vol. 2, Núm. 4
2020
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A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by Treg cells
Nature, Vol. 583, Núm. 7816, pp. 447-452
2019
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Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases
Nature Genetics, Vol. 51, Núm. 10, pp. 1486-1493
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GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways
Nature Communications, Vol. 10, Núm. 1
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Histone modifications underlie monocyte dysregulation in patients with systemic sclerosis, underlining the treatment potential of epigenetic targeting
Annals of the Rheumatic Diseases, Vol. 78, Núm. 4, pp. 529-538
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Low RUNX3 expression alters dendritic cell function in patients with systemic sclerosis and contributes to enhanced fibrosis
Annals of the Rheumatic Diseases, Vol. 78, Núm. 9, pp. 1249-1259
2018
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Coloc-stats: A unified web interface to perform colocalization analysis of genomic features
Nucleic Acids Research, Vol. 46, Núm. W1, pp. W186-W193
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Gene expression variability across cells and species shapes innate immunity
Nature, Vol. 563, Núm. 7730, pp. 197-202
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Gene-level association analysis of systemic sclerosis: A comparison of African-Americans and White populations
PLoS ONE, Vol. 13, Núm. 1
2017
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Association of MicroRNA-618 Expression With Altered Frequency and Activation of Plasmacytoid Dendritic Cells in Patients With Systemic Sclerosis
Arthritis and Rheumatology, Vol. 69, Núm. 9, pp. 1891-1902
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Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets
Nature Genetics, Vol. 49, Núm. 3, pp. 416-425