Publicacións nas que colabora con ANTONIO ESPINOSA UBEDA (25)

2013

  1. Antiproliferative activity, cell cycle, and apoptosis studies of a series of 6-substituted 9H-purin-9-yl-pyridinium derivatives on a human cervical carcinoma cell line

    ChemMedChem, Vol. 8, Núm. 8, pp. 1266-1269

2008

  1. Anticancer activity of (1,2,3,5-tetrahydro-4,1-benzoxazepine-3-yl)-pyrimidines and -purines against the MCF-7 cell line: Preliminary cDNA microarray studies

    Bioorganic and Medicinal Chemistry Letters, Vol. 18, Núm. 4, pp. 1457-1460

  2. Design, synthesis and anticancer activity against the MCF-7 cell line of benzo-fused 1,4-dihetero seven- and six-membered tethered pyrimidines and purines

    Current Medicinal Chemistry, Vol. 15, Núm. 25, pp. 2614-2631

  3. From 5-fluorouracil acyclonucleosides to benzo-fused six- and seven-membered rings linked to pyrimidine and purine bases: The shift from differentiating anticancer agents to apoptotic inducers

    Expert Opinion on Drug Discovery, Vol. 3, Núm. 10, pp. 1223-1235

  4. Synthesis and anticancer activity of (R,S)-9-(2,3-dihydro-1,4-benzoxathiin- 3-ylmethyl)-9H-purines

    ChemMedChem, Vol. 3, Núm. 1, pp. 127-135

2007

  1. 5-fluorouracil derivatives induce differentiation mediated by tubulin and HLA class I modulation

    Medicinal Chemistry, Vol. 3, Núm. 3, pp. 233-239

  2. A synthetic uracil derivative with antitumor activity through decreasing cyclin D1 and Cdk1, and increasing p21 and p27 in MCF-7 cells

    Breast Cancer Research and Treatment, Vol. 105, Núm. 3, pp. 237-246

  3. Corrigendum to "Synthesis and reactivity of (RS)-6-chloro-7- or 9-(1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl)-7H- or 9H-purines bearing a nitrobenzenesulfonyl group on the nitrogen atom". [Tetrahedron 63 (2007) 5274] (DOI:10.1016/j.tet.2007.03.155)

    Tetrahedron

  4. QSAR as a tool for the development of potent antiproliferative agents by inhibition of choline kinase

    Current Computer-Aided Drug Design, Vol. 3, Núm. 4, pp. 297-313

  5. Synthesis and reactivity of (RS)-6-chloro-7- or 9-(1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl)-7H- or 9H-purines bearing a nitrobenzenesulfonyl group on the nitrogen atom

    Tetrahedron, Vol. 63, Núm. 24, pp. 5274-5286

2006

  1. (Q)SAR studies to design new human choline kinase inhibitors as antiproliferative drugs

    Current Medicinal Chemistry, Vol. 13, Núm. 11, pp. 1231-1248

  2. Study of the factors that control the ratio of the products between 5-fluorouracil, uracil, and tetrahydrobenzoxazepine O,O-acetals bearing electron-withdrawing groups on the nitrogen atom

    Journal of Organic Chemistry, Vol. 71, Núm. 3, pp. 1043-1054

  3. Synthesis and anticancer activity studies of novel 1-(2,3-dihydro-5H-1,4-benzodioxepin-3-yl)uracil and (6′-substituted)-7- or 9-(2,3-dihydro-5H-1,4-benzodioxepin-3-yl)-7H- or 9H-purines

    Tetrahedron, Vol. 62, Núm. 50, pp. 11724-11733

2005

  1. 1H and 13C spectral assignment of symmetrical bis[(4-aminosubstituted)quinolinium] derivatives

    Magnetic Resonance in Chemistry, Vol. 43, Núm. 12, pp. 1066-1071

  2. Symmetrical bis-quinolinium compounds: New human choline kinase inhibitors with antiproliferative activity against the HT-29 cell line

    Journal of Medicinal Chemistry, Vol. 48, Núm. 9, pp. 3354-3363

  3. Towards a model for the inhibition of choline kinase by a new type of inhibitor

    European Journal of Medicinal Chemistry, Vol. 40, Núm. 3, pp. 315-319

2004

  1. Actual targets in cytodifferentiation cancer therapy

    Current Topics in Medicinal Chemistry, Vol. 4, Núm. 2, pp. 175-202

  2. Influence of the linker in bispyridium compounds on the inhibition of human choline kinase

    Journal of Medicinal Chemistry, Vol. 47, Núm. 22, pp. 5433-5440

  3. Substituent effects on the reaction mode between 2-hydroxybenzyl alcohol derivatives and MEM chloride: Synthesis and mechanistic aspects of seven- and ten-membered benzo-fused O,O-acetals

    Tetrahedron, Vol. 60, Núm. 50, pp. 11453-11464

  4. Synthesis of tetrahydrobenzoxazepine acetals with electron-withdrawing groups on the nitrogen atom. Novel scaffolds endowed with anticancer activity against breast cancer cells

    Tetrahedron, Vol. 60, Núm. 50, pp. 11547-11557