Publicaciones en las que colabora con ANA CONEJO GARCÍA (19)

2021

  1. Design, synthesis, HER2 inhibition and anticancer evaluation of new substituted 1,5-dihydro-4,1-benzoxazepines

    Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 36, Núm. 1, pp. 1553-1563

2018

  1. Enhancement of tumor cell death by combining gef gene mediated therapy and new 1,4-benzoxazepin-2,6-dichloropurine derivatives in breast cancer cells

    Frontiers in Pharmacology, Vol. 9, Núm. JUL

2017

  1. 1-(Benzenesulfonyl)-1,5-dihydro-4,1-benzoxazepine as a new scaffold for the design of antitumor compounds

    Future Medicinal Chemistry, Vol. 9, Núm. 11, pp. 1129-1140

  2. Antitumoral activity of 1,2-diaminocyclohexane derivatives in breast, colon and skin human cancer cells

    Future Medicinal Chemistry, Vol. 9, Núm. 3, pp. 293-302

2015

  1. P-Nitrobenzenesulfonamides and their fluorescent dansylsulfonamides derived from N-alkylated o-(purine-methyl)anilines as novel antitumour agents

    RSC Advances, Vol. 5, Núm. 93, pp. 76615-76619

2014

  1. Anti-proliferative activity of 2,6-dichloro-9- or 7-(ethoxycarbonylmethyl)- 9H- or 7H-purines against several human solid tumour cell lines

    European Journal of Medicinal Chemistry, Vol. 76, pp. 118-124

  2. HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib small compound

    Oncotarget, Vol. 5, Núm. 11, pp. 3590-3606

2013

  1. Bozepinib, a novel small antitumor agent, induces PKR-mediated apoptosis and synergizes with IFNα triggering apoptosis, autophagy and senescence

    Drug Design, Development and Therapy, Vol. 7, pp. 1301-1313

  2. Chromatographic enantioresolution of six purine derivatives endowed with anti-human breast cancer activity

    Chromatographia, Vol. 76, Núm. 9-10, pp. 475-482

  3. Enantiospecific synthesis of heterocycles linked to purines: Different apoptosis modulation of enantiomers in breast cancer cells

    Current Medicinal Chemistry, Vol. 20, Núm. 38, pp. 4924-4934

2012

  1. The selective cytotoxic activity in breast cancer cells by an anthranilic alcohol-derived acyclic 5-fluorouracil O,N-acetal is mediated by endoplasmic reticulum stress-induced apoptosis

    European Journal of Medicinal Chemistry, Vol. 50, pp. 376-382

2011

  1. New (RS)-benzoxazepin-purines with antitumour activity: The chiral switch from (RS)-2,6-dichloro-9-[1-(p-nitrobenzenesulfonyl)-1,2,3,5-tetrahydro-4,1- benzoxazepin-3-yl]-9H-purine

    European Journal of Medicinal Chemistry, Vol. 46, Núm. 1, pp. 249-258

  2. Novel substituted quinazolines for potent EGFR tyrosine kinase inhibitors

    Current Medicinal Chemistry, Vol. 18, Núm. 7, pp. 943-963

  3. Synthesis and Anticancer Activity of the (R,S)-Benzofused 1,5-Oxathiepine Moiety Tethered to Purines through Alkylidenoxy Linkers

    ChemMedChem, Vol. 6, Núm. 10, pp. 1854-1859

  4. Synthesis and anticancer activity of (RS)-9-(2,3-dihydro-1,4- benzoxaheteroin-2-ylmethyl)-9H-purines

    European Journal of Medicinal Chemistry, Vol. 46, Núm. 9, pp. 3795-3801

2010

  1. Synthesis of purine derivatives as scaffolds for a diversity of biological activities

    Current Organic Chemistry, Vol. 14, Núm. 20, pp. 2463-2482

2009

  1. Homochiral drugs: A demanding tendency of the pharmaceutical industry

    Current Medicinal Chemistry, Vol. 16, Núm. 16, pp. 2064-2074

2008

  1. Regiospecific microwave-assisted synthesis and cytotoxic activity against human breast cancer cells of (RS)-6-substituted-7- or 9-(2,3-dihydro-5H-1,4-benzodioxepin-3-yl)-7H- or -9H-purines

    European Journal of Medicinal Chemistry, Vol. 43, Núm. 8, pp. 1742-1748

  2. Synthesis and anticancer activity of (R,S)-9-(2,3-dihydro-1,4-benzoxathiin- 3-ylmethyl)-9H-purines

    ChemMedChem, Vol. 3, Núm. 1, pp. 127-135