BIOFISICA Y BIOTECNOLOGIA MOLECULAR
BIOFISICA Y BIOTECNOLOGIA MOLE
ENCARNACIÓN
MEDINA CARMONA
PROGRAMA INVESTIGACION RAMON Y CAJAL
Publicaciones en las que colabora con ENCARNACIÓN MEDINA CARMONA (10)
2019
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Insight into the specificity and severity of pathogenic mechanisms associated with missense mutations through experimental and structural perturbation analyses
Human Molecular Genetics, Vol. 28, Núm. 1, pp. 1-15
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Phosphorylation compromises FAD binding and intracellular stability of wild-type and cancer-associated NQO1: Insights into flavo-proteome stability
International Journal of Biological Macromolecules, Vol. 125, pp. 1275-1288
2018
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Second Generation of Mannich Base-Type Derivatives with in Vivo Activity against Trypanosoma cruzi
Journal of Medicinal Chemistry, Vol. 61, Núm. 13, pp. 5643-5663
2017
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A mechanism for cancer-associated inactivation of NQO1 due to P187S and its reactivation by the consensus mutation H80R
FEBS Letters, Vol. 591, Núm. 18, pp. 2826-2835
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Enhanced vulnerability of human proteins towards disease-associated inactivation through divergent evolution
Human Molecular Genetics, Vol. 26, Núm. 18, pp. 3531-3544
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Site-to-site interdomain communication may mediate different loss-of-function mechanisms in a cancer-associated NQO1 polymorphism
Scientific Reports, Vol. 7
2016
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Conformational dynamics is key to understanding loss-of-function of NQO1 cancer-associated polymorphisms and its correction by pharmacological ligands
Scientific Reports, Vol. 6
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Erratum: Conformational dynamics is key to understanding loss-of-function of NQO1 cancer-associated polymorphisms and its correction by pharmacological ligands (Scientific Reports (2016) 6 (20331) DOI: 10.1038/srep20331)
Scientific Reports
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Natural small molecules as stabilizers and activators of cancer-associated NQO1 polymorphisms
Current Drug Targets, Vol. 17, Núm. 13, pp. 1506-1514
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The chondroitin sulfate/dermatan sulfate 4-O-endosulfatase from marine bacterium Vibrio sp FC509 is a dimeric species: Biophysical characterization of an endosulfatase
Biochimie, Vol. 131, pp. 85-95