Publications by the researcher in collaboration with BELÉN RUBIO RUIZ (15)

2024

  1. Hydroxytyrosyl punicate: A first overview of a novel phenolipid with antiproliferative and antitrypanosomal activity

    Journal of Functional Foods, Vol. 117

2023

  1. N-aryltetrahydroisoquinoline derivatives as HA-CD44 interaction inhibitors: Design, synthesis, computational studies, and antitumor effect

    European Journal of Medicinal Chemistry, Vol. 258

2022

  1. Selective Anticancer Therapy Based on a HA-CD44 Interaction Inhibitor Loaded on Polymeric Nanoparticles

    Pharmaceutics, Vol. 14, Núm. 4

2021

  1. Recent advances in the design of choline kinase α inhibitors and the molecular basis of their inhibition

    Medicinal Research Reviews, Vol. 41, Núm. 2, pp. 902-927

2017

  1. Choline kinase inhibition and docking studies of a series of 6-(benzylthio)-9H-purin-9-yl-pyridinium derivatives

    Medicinal Chemistry Research, Vol. 26, Núm. 11, pp. 2809-2815

  2. Lysophosphatidylcholine Regulates Sexual Stage Differentiation in the Human Malaria Parasite Plasmodium falciparum

    Cell, Vol. 171, Núm. 7, pp. 1532-1544.e15

2016

  1. Plasmodium falciparum Choline Kinase Inhibition Leads to a Major Decrease in Phosphatidylethanolamine Causing Parasite Death

    Scientific Reports, Vol. 6

2014

  1. Discovery of a new binding site on human choline kinase α1: Design, synthesis, crystallographic studies, and biological evaluation of asymmetrical bispyridinium derivatives

    Journal of Medicinal Chemistry, Vol. 57, Núm. 2, pp. 507-515

  2. In vitro antiplasmodial and cytotoxic activities of asymmetrical pyridinium derivatives

    European Journal of Medicinal Chemistry, Vol. 85, pp. 289-292

  3. NMR spectroscopic characterization of new nonsymmetrical bispyridinium choline kinase inhibitors

    Magnetic Resonance in Chemistry

2013

  1. Antiproliferative activity, cell cycle, and apoptosis studies of a series of 6-substituted 9H-purin-9-yl-pyridinium derivatives on a human cervical carcinoma cell line

    ChemMedChem, Vol. 8, Núm. 8, pp. 1266-1269

  2. Determination of potential scaffolds for human choline kinase α1 by chemical deconvolution studies

    ChemBioChem, Vol. 14, Núm. 11, pp. 1291-1295

  3. The mechanism of allosteric coupling in choline kinase α1 revealed by the action of a rationally designed inhibitor

    Angewandte Chemie - International Edition, Vol. 52, Núm. 17, pp. 4582-4586

2012

  1. 1H and 13C NMR spectral assignments of pyridinium salts linked to a N-9 or N-3 adenine moiety

    Magnetic Resonance in Chemistry, Vol. 50, Núm. 6, pp. 466-469

  2. Design, synthesis, theoretical calculations and biological evaluation of new non-symmetrical choline kinase inhibitors

    European Journal of Medicinal Chemistry, Vol. 50, pp. 154-162