ANA
CONEJO GARCÍA
CATEDRÁTICA DE UNIVERSIDAD
JOAQUÍN MARÍA
CAMPOS ROSA
Ikertzailea null-(e)tik
JOAQUÍN MARÍA CAMPOS ROSA-rekin lankidetzan egindako argitalpenak (44)
2024
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Synthesis and Anti-Diabetic Activity of an 8-Purine Derivative as a Novel DPP-4 Inhibitor in Obese Diabetic Zücker Rats
Drug Design, Development and Therapy, Vol. 18, pp. 1133-1141
2023
2021
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Design, synthesis, HER2 inhibition and anticancer evaluation of new substituted 1,5-dihydro-4,1-benzoxazepines
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 36, Núm. 1, pp. 1553-1563
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Development of bozepinib-loaded nanocapsules for nose-to-brain delivery: Preclinical evaluation in glioblastoma
Nanomedicine, Vol. 16, Núm. 23, pp. 2095-2115
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New insights into cytotoxic mechanisms of bozepinib against glioblastoma
European Journal of Pharmaceutical Sciences, Vol. 162
2018
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Enhancement of tumor cell death by combining gef gene mediated therapy and new 1,4-benzoxazepin-2,6-dichloropurine derivatives in breast cancer cells
Frontiers in Pharmacology, Vol. 9, Núm. JUL
2017
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1-(Benzenesulfonyl)-1,5-dihydro-4,1-benzoxazepine as a new scaffold for the design of antitumor compounds
Future Medicinal Chemistry, Vol. 9, Núm. 11, pp. 1129-1140
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Antitumoral activity of 1,2-diaminocyclohexane derivatives in breast, colon and skin human cancer cells
Future Medicinal Chemistry, Vol. 9, Núm. 3, pp. 293-302
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Synthesis of 1,4-benzoxathiin-9H-purine derivatives as antiproliferative agents
Targets in Heterocyclic Systems, Vol. 21, pp. 372-388
2016
2015
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P-Nitrobenzenesulfonamides and their fluorescent dansylsulfonamides derived from N-alkylated o-(purine-methyl)anilines as novel antitumour agents
RSC Advances, Vol. 5, Núm. 93, pp. 76615-76619
2014
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Anti-proliferative activity of 2,6-dichloro-9- or 7-(ethoxycarbonylmethyl)- 9H- or 7H-purines against several human solid tumour cell lines
European Journal of Medicinal Chemistry, Vol. 76, pp. 118-124
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HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib small compound
Oncotarget, Vol. 5, Núm. 11, pp. 3590-3606
2013
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Bozepinib, a novel small antitumor agent, induces PKR-mediated apoptosis and synergizes with IFNα triggering apoptosis, autophagy and senescence
Drug Design, Development and Therapy, Vol. 7, pp. 1301-1313
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Chromatographic enantioresolution of six purine derivatives endowed with anti-human breast cancer activity
Chromatographia, Vol. 76, Núm. 9-10, pp. 475-482
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Enantiospecific synthesis of heterocycles linked to purines: Different apoptosis modulation of enantiomers in breast cancer cells
Current Medicinal Chemistry, Vol. 20, Núm. 38, pp. 4924-4934
2012
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The selective cytotoxic activity in breast cancer cells by an anthranilic alcohol-derived acyclic 5-fluorouracil O,N-acetal is mediated by endoplasmic reticulum stress-induced apoptosis
European Journal of Medicinal Chemistry, Vol. 50, pp. 376-382
2011
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Homodimeric bis-quaternary heterocyclic ammonium salts as potent acetyl- and butyrylcholinesterase inhibitors: A systematic investigation of the influence of linker and cationic heads over affinity and selectivity
Journal of Medicinal Chemistry, Vol. 54, Núm. 8, pp. 2627-2645
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New (RS)-benzoxazepin-purines with antitumour activity: The chiral switch from (RS)-2,6-dichloro-9-[1-(p-nitrobenzenesulfonyl)-1,2,3,5-tetrahydro-4,1- benzoxazepin-3-yl]-9H-purine
European Journal of Medicinal Chemistry, Vol. 46, Núm. 1, pp. 249-258
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Novel substituted quinazolines for potent EGFR tyrosine kinase inhibitors
Current Medicinal Chemistry, Vol. 18, Núm. 7, pp. 943-963