Publicaciones (64) Publicaciones de ANA CONEJO GARCÍA

2023

  1. N-aryltetrahydroisoquinoline derivatives as HA-CD44 interaction inhibitors: Design, synthesis, computational studies, and antitumor effect

    European Journal of Medicinal Chemistry, Vol. 258

  2. Preclinical evaluation of bozepinib in bladder cancer cell lines: modulation of the NPP1 enzyme

    Purinergic Signalling

2022

  1. Selective Anticancer Therapy Based on a HA-CD44 Interaction Inhibitor Loaded on Polymeric Nanoparticles

    Pharmaceutics, Vol. 14, Núm. 4

2021

  1. Design, synthesis, HER2 inhibition and anticancer evaluation of new substituted 1,5-dihydro-4,1-benzoxazepines

    Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 36, Núm. 1, pp. 1553-1563

  2. Development of bozepinib-loaded nanocapsules for nose-to-brain delivery: Preclinical evaluation in glioblastoma

    Nanomedicine, Vol. 16, Núm. 23, pp. 2095-2115

  3. New insights into cytotoxic mechanisms of bozepinib against glioblastoma

    European Journal of Pharmaceutical Sciences, Vol. 162

  4. Recent advances in the design of choline kinase α inhibitors and the molecular basis of their inhibition

    Medicinal Research Reviews, Vol. 41, Núm. 2, pp. 902-927

2020

  1. Bozepinib: A Promising Selective Derivative Targeting Breast Cancer Stem Cells

    Translational Research in Cancer (IntechOpen)

2018

  1. Enhancement of tumor cell death by combining gef gene mediated therapy and new 1,4-benzoxazepin-2,6-dichloropurine derivatives in breast cancer cells

    Frontiers in Pharmacology, Vol. 9, Núm. JUL

2017

  1. 1-(Benzenesulfonyl)-1,5-dihydro-4,1-benzoxazepine as a new scaffold for the design of antitumor compounds

    Future Medicinal Chemistry, Vol. 9, Núm. 11, pp. 1129-1140

  2. Antitumoral activity of 1,2-diaminocyclohexane derivatives in breast, colon and skin human cancer cells

    Future Medicinal Chemistry, Vol. 9, Núm. 3, pp. 293-302

  3. Choline kinase inhibition and docking studies of a series of 6-(benzylthio)-9H-purin-9-yl-pyridinium derivatives

    Medicinal Chemistry Research, Vol. 26, Núm. 11, pp. 2809-2815

  4. Lysophosphatidylcholine Regulates Sexual Stage Differentiation in the Human Malaria Parasite Plasmodium falciparum

    Cell, Vol. 171, Núm. 7, pp. 1532-1544.e15

  5. Synthesis of 1,4-benzoxathiin-9H-purine derivatives as antiproliferative agents

    Targets in Heterocyclic Systems, Vol. 21, pp. 372-388

2016

  1. 1H and 13C NMR spectral data of p-nitrobenzenesulfonamides and dansylsulfonamides derived from N-alkylated o-(Purinemethyl)anilines

    Magnetic Resonance in Chemistry

  2. Plasmodium falciparum Choline Kinase Inhibition Leads to a Major Decrease in Phosphatidylethanolamine Causing Parasite Death

    Scientific Reports, Vol. 6

2015

  1. P-Nitrobenzenesulfonamides and their fluorescent dansylsulfonamides derived from N-alkylated o-(purine-methyl)anilines as novel antitumour agents

    RSC Advances, Vol. 5, Núm. 93, pp. 76615-76619

2014

  1. Anti-proliferative activity of 2,6-dichloro-9- or 7-(ethoxycarbonylmethyl)- 9H- or 7H-purines against several human solid tumour cell lines

    European Journal of Medicinal Chemistry, Vol. 76, pp. 118-124

  2. Discovery of a new binding site on human choline kinase α1: Design, synthesis, crystallographic studies, and biological evaluation of asymmetrical bispyridinium derivatives

    Journal of Medicinal Chemistry, Vol. 57, Núm. 2, pp. 507-515

  3. HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib small compound

    Oncotarget, Vol. 5, Núm. 11, pp. 3590-3606