Publicacions en col·laboració amb investigadors/es de Universidad de Zaragoza (7)

2017

  1. Choline kinase inhibition and docking studies of a series of 6-(benzylthio)-9H-purin-9-yl-pyridinium derivatives

    Medicinal Chemistry Research, Vol. 26, Núm. 11, pp. 2809-2815

2016

  1. Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1)

    Scientific Reports, Vol. 6

  2. Plasmodium falciparum Choline Kinase Inhibition Leads to a Major Decrease in Phosphatidylethanolamine Causing Parasite Death

    Scientific Reports, Vol. 6

2015

  1. Pharmacophore-Based Virtual Screening to Discover New Active Compounds for Human Choline Kinase α1

    Molecular Informatics, Vol. 34, Núm. 6-7, pp. 458-466

2014

  1. Choline kinase active site provides features for designing versatile inhibitors

    Current Topics in Medicinal Chemistry, Vol. 14, Núm. 23, pp. 2684-2693

2013

  1. Determination of potential scaffolds for human choline kinase α1 by chemical deconvolution studies

    ChemBioChem, Vol. 14, Núm. 11, pp. 1291-1295

  2. The mechanism of allosteric coupling in choline kinase α1 revealed by the action of a rationally designed inhibitor

    Angewandte Chemie - International Edition, Vol. 52, Núm. 17, pp. 4582-4586