ANTONIO
ENTRENA GUADIX
Investigador en el periodo 2009-2018
Università di Perugia
Perugia, ItaliaPublicaciones en colaboración con investigadores/as de Università di Perugia (9)
2018
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Lead optimization-hit expansion of new asymmetrical pyridinium/quinolinium compounds as choline kinase α1 inhibitors
Future Medicinal Chemistry, Vol. 10, Núm. 15, pp. 1769-1786
2015
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Pharmacophore-Based Virtual Screening to Discover New Active Compounds for Human Choline Kinase α1
Molecular Informatics, Vol. 34, Núm. 6-7, pp. 458-466
2014
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Choline kinase active site provides features for designing versatile inhibitors
Current Topics in Medicinal Chemistry, Vol. 14, Núm. 23, pp. 2684-2693
2006
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Back door modulation of the farnesoid X receptor: Design, synthesis, and biological evaluation of a series of side chain modified chenodeoxycholic acid derivatives
Journal of Medicinal Chemistry, Vol. 49, Núm. 14, pp. 4208-4215
2005
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Molecular dynamics simulation of the ligand binding domain of farnesoid X receptor. Insights into helix-12 stability and coactivator peptide stabilization in response to agonist binding
Journal of Medicinal Chemistry, Vol. 48, Núm. 9, pp. 3251-3259
2004
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Bile acid derivatives as ligands of the farnesoid X receptor. Synthesis, evaluation, and structure - Activity relationship of a series of body and side chain modified analogues of chenodeoxycholic acid
Journal of Medicinal Chemistry, Vol. 47, Núm. 18, pp. 4559-4569
2003
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Binding mode of 6ECDCA, a potent bile acid agonist of the farnesoid X receptor (FXR)
Bioorganic and Medicinal Chemistry Letters, Vol. 13, Núm. 11, pp. 1865-1868
2001
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Conformational analysis of carboxyphenylglycine (CPG) derivatives: Insight into bioactive and bioselective conformations of group-I mGluRs antagonists
Farmaco, Vol. 56, Núm. 11, pp. 891-898
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QSAR and molecular modeling studies of baclofen analogues as GABAB agonists. Insights into the role of the aromatic moiety in GABAB binding and activation
Journal of Medicinal Chemistry, Vol. 44, Núm. 11, pp. 1827-1832