BELÉN
RUBIO RUIZ
PROFESORA TITULAR DE UNIVERSIDAD
ANTONIO
ESPINOSA UBEDA
Investigador en el periodo 2002-2011
Publicaciones en las que colabora con ANTONIO ESPINOSA UBEDA (8)
2017
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Choline kinase inhibition and docking studies of a series of 6-(benzylthio)-9H-purin-9-yl-pyridinium derivatives
Medicinal Chemistry Research, Vol. 26, Núm. 11, pp. 2809-2815
2014
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Discovery of a new binding site on human choline kinase α1: Design, synthesis, crystallographic studies, and biological evaluation of asymmetrical bispyridinium derivatives
Journal of Medicinal Chemistry, Vol. 57, Núm. 2, pp. 507-515
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In vitro antiplasmodial and cytotoxic activities of asymmetrical pyridinium derivatives
European Journal of Medicinal Chemistry, Vol. 85, pp. 289-292
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NMR spectroscopic characterization of new nonsymmetrical bispyridinium choline kinase inhibitors
Magnetic Resonance in Chemistry
2013
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Antiproliferative activity, cell cycle, and apoptosis studies of a series of 6-substituted 9H-purin-9-yl-pyridinium derivatives on a human cervical carcinoma cell line
ChemMedChem, Vol. 8, Núm. 8, pp. 1266-1269
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The mechanism of allosteric coupling in choline kinase α1 revealed by the action of a rationally designed inhibitor
Angewandte Chemie - International Edition, Vol. 52, Núm. 17, pp. 4582-4586
2012
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1H and 13C NMR spectral assignments of pyridinium salts linked to a N-9 or N-3 adenine moiety
Magnetic Resonance in Chemistry, Vol. 50, Núm. 6, pp. 466-469
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Design, synthesis, theoretical calculations and biological evaluation of new non-symmetrical choline kinase inhibitors
European Journal of Medicinal Chemistry, Vol. 50, pp. 154-162