BELÉN
RUBIO RUIZ
PROFESORA TITULAR DE UNIVERSIDAD
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University of Edinburgh
Edimburgo, Reino UnidoPublicaciones en colaboración con investigadores/as de University of Edinburgh (19)
2023
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In Cellulo Bioorthogonal Catalysis by Encapsulated AuPd Nanoalloys: Overcoming Intracellular Deactivation
Nano Letters, Vol. 23, Núm. 3, pp. 804-811
2022
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A 5-FU Precursor Designed to Evade Anabolic and Catabolic Drug Pathways and Activated by Pd Chemistry in Vitro and in Vivo
Journal of Medicinal Chemistry, Vol. 65, Núm. 1, pp. 552-561
2021
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A minimally-masked inactive prodrug of panobinostat that is bioorthogonally activated by gold chemistry
Bioorganic and Medicinal Chemistry, Vol. 41
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Nondestructive production of exosomes loaded with ultrathin palladium nanosheets for targeted bio-orthogonal catalysis
Nature Protocols, Vol. 16, Núm. 1, pp. 131-163
2020
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Bioorthogonal Uncaging of Cytotoxic Paclitaxel through Pd Nanosheet-Hydrogel Frameworks
Journal of medicinal chemistry, Vol. 63, Núm. 17, pp. 9650-9659
2019
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Cancer-derived exosomes loaded with ultrathin palladium nanosheets for targeted bioorthogonal catalysis
Nature Catalysis, Vol. 2, Núm. 10, pp. 864-872
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Design and manufacture of functional catalyst-carrier structures for the bioorthogonal activation of anticancer agents
New Journal of Chemistry, Vol. 43, Núm. 3, pp. 1449-1458
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Purine derivatives with heterocyclic moieties and related analogs as new antitumor agents
Future Medicinal Chemistry, Vol. 11, Núm. 2, pp. 83-95
2018
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Bioorthogonal Uncaging of the Active Metabolite of Irinotecan by Palladium-Functionalized Microdevices
Chemistry - A European Journal, Vol. 24, Núm. 63, pp. 16783-16790
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Bright insights into palladium-triggered local chemotherapy
Chemical Science, Vol. 9, Núm. 37, pp. 7354-7361
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High-Precision Photothermal Ablation Using Biocompatible Palladium Nanoparticles and Laser Scanning Microscopy
ACS Applied Materials and Interfaces, Vol. 10, Núm. 4, pp. 3341-3348
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Pharmaco-genomic investigations of organo-iridium anticancer complexes reveal novel mechanism of action
Metallomics, Vol. 10, Núm. 1, pp. 93-107
2017
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Gold-Triggered Uncaging Chemistry in Living Systems
Angewandte Chemie - International Edition, Vol. 56, Núm. 41, pp. 12548-12552
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Lysophosphatidylcholine Regulates Sexual Stage Differentiation in the Human Malaria Parasite Plasmodium falciparum
Cell, Vol. 171, Núm. 7, pp. 1532-1544.e15
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Masking strategies for the bioorthogonal release of anticancer glycosides
Coupling and Decoupling of Diverse Molecular Units in Glycosciences (Springer International Publishing), pp. 269-298
2016
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Efficient Palladium-Triggered Release of Vorinostat from a Bioorthogonal Precursor
Journal of Medicinal Chemistry, Vol. 59, Núm. 21, pp. 9974-9980
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Plasmodium falciparum Choline Kinase Inhibition Leads to a Major Decrease in Phosphatidylethanolamine Causing Parasite Death
Scientific Reports, Vol. 6
2014
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In vitro antiplasmodial and cytotoxic activities of asymmetrical pyridinium derivatives
European Journal of Medicinal Chemistry, Vol. 85, pp. 289-292
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N-alkynyl derivatives of 5-fluorouracil: Susceptibility to palladium-mediated dealkylation and toxigenicity in cancer cell culture
Frontiers in Chemistry, Vol. 2, Núm. JUL