Publicaciones en colaboración con investigadores/as de University of Edinburgh (19)

2023

  1. In Cellulo Bioorthogonal Catalysis by Encapsulated AuPd Nanoalloys: Overcoming Intracellular Deactivation

    Nano Letters, Vol. 23, Núm. 3, pp. 804-811

2022

  1. A 5-FU Precursor Designed to Evade Anabolic and Catabolic Drug Pathways and Activated by Pd Chemistry in Vitro and in Vivo

    Journal of Medicinal Chemistry, Vol. 65, Núm. 1, pp. 552-561

2021

  1. A minimally-masked inactive prodrug of panobinostat that is bioorthogonally activated by gold chemistry

    Bioorganic and Medicinal Chemistry, Vol. 41

  2. Nondestructive production of exosomes loaded with ultrathin palladium nanosheets for targeted bio-orthogonal catalysis

    Nature Protocols, Vol. 16, Núm. 1, pp. 131-163

2020

  1. Bioorthogonal Uncaging of Cytotoxic Paclitaxel through Pd Nanosheet-Hydrogel Frameworks

    Journal of medicinal chemistry, Vol. 63, Núm. 17, pp. 9650-9659

2019

  1. Cancer-derived exosomes loaded with ultrathin palladium nanosheets for targeted bioorthogonal catalysis

    Nature Catalysis, Vol. 2, Núm. 10, pp. 864-872

  2. Design and manufacture of functional catalyst-carrier structures for the bioorthogonal activation of anticancer agents

    New Journal of Chemistry, Vol. 43, Núm. 3, pp. 1449-1458

  3. Purine derivatives with heterocyclic moieties and related analogs as new antitumor agents

    Future Medicinal Chemistry, Vol. 11, Núm. 2, pp. 83-95

2018

  1. Bioorthogonal Uncaging of the Active Metabolite of Irinotecan by Palladium-Functionalized Microdevices

    Chemistry - A European Journal, Vol. 24, Núm. 63, pp. 16783-16790

  2. Bright insights into palladium-triggered local chemotherapy

    Chemical Science, Vol. 9, Núm. 37, pp. 7354-7361

  3. High-Precision Photothermal Ablation Using Biocompatible Palladium Nanoparticles and Laser Scanning Microscopy

    ACS Applied Materials and Interfaces, Vol. 10, Núm. 4, pp. 3341-3348

  4. Pharmaco-genomic investigations of organo-iridium anticancer complexes reveal novel mechanism of action

    Metallomics, Vol. 10, Núm. 1, pp. 93-107

2017

  1. Gold-Triggered Uncaging Chemistry in Living Systems

    Angewandte Chemie - International Edition, Vol. 56, Núm. 41, pp. 12548-12552

  2. Lysophosphatidylcholine Regulates Sexual Stage Differentiation in the Human Malaria Parasite Plasmodium falciparum

    Cell, Vol. 171, Núm. 7, pp. 1532-1544.e15

  3. Masking strategies for the bioorthogonal release of anticancer glycosides

    Coupling and Decoupling of Diverse Molecular Units in Glycosciences (Springer International Publishing), pp. 269-298

2016

  1. Efficient Palladium-Triggered Release of Vorinostat from a Bioorthogonal Precursor

    Journal of Medicinal Chemistry, Vol. 59, Núm. 21, pp. 9974-9980

  2. Plasmodium falciparum Choline Kinase Inhibition Leads to a Major Decrease in Phosphatidylethanolamine Causing Parasite Death

    Scientific Reports, Vol. 6

2014

  1. In vitro antiplasmodial and cytotoxic activities of asymmetrical pyridinium derivatives

    European Journal of Medicinal Chemistry, Vol. 85, pp. 289-292

  2. N-alkynyl derivatives of 5-fluorouracil: Susceptibility to palladium-mediated dealkylation and toxigenicity in cancer cell culture

    Frontiers in Chemistry, Vol. 2, Núm. JUL