Publications by the researcher in collaboration with FRANCISCO OLMO ARÉVALO (23)

2017

  1. Simple dialkyl pyrazole-3,5-dicarboxylates show in vitro and in vivo activity against disease-causing trypanosomatids

    Parasitology, Vol. 144, Núm. 9, pp. 1133-1143

  2. Tetradentate polyamines as efficient metallodrugs for Chagas disease treatment in murine model

    Journal of Chemotherapy, Vol. 29, Núm. 2, pp. 83-93

2016

  1. Effective anti-leishmanial activity of minimalist squaramide-based compounds

    Experimental Parasitology, Vol. 170, pp. 36-49

  2. In vitro and in vivo identification of tetradentated polyamine complexes as highly efficient metallodrugs against Trypanosoma cruzi

    Experimental Parasitology, Vol. 164, pp. 20-30

2015

  1. An invitro iron superoxide dismutase inhibitor decreases the parasitemia levels of Trypanosoma cruzi in BALB/c mouse model during acute phase

    International Journal for Parasitology: Drugs and Drug Resistance, Vol. 5, Núm. 3, pp. 110-116

  2. Prospects of an alternative treatment against Trypanosoma cruzi based on abietic acid derivatives show promising results in Balb/c mouse model

    European Journal of Medicinal Chemistry, Vol. 89, pp. 863-890

  3. Synthesis and evaluation of in vitro and in vivo trypanocidal properties of a new imidazole-containing nitrophthalazine derivative

    European Journal of Medicinal Chemistry, Vol. 106, pp. 106-119

2014

  1. In vitro leishmanicidal activity of pyrazole-containing polyamine macrocycles which inhibit the Fe-SOD enzyme of Leishmania infantum and Leishmania braziliensis species

    Parasitology, Vol. 141, Núm. 8, pp. 1031-1043

  2. Specific primers design based on the superoxide dismutase b gene for Trypanosoma cruzi as a screening tool: Validation method using strains from Colombia classified according to their discrete typing unit

    Asian Pacific Journal of Tropical Medicine, Vol. 7, Núm. 11, pp. 854-859

  3. Synthesis and biological evaluation of N, N ′-squaramides with high in vivo efficacy and low toxicity: Toward a low-cost drug against Chagas disease

    Journal of Medicinal Chemistry, Vol. 57, Núm. 3, pp. 987-999

  4. Synthetic single and double aza-scorpiand macrocycles acting as inhibitors of the antioxidant enzymes iron superoxide dismutase and trypanothione reductase in Trypanosoma cruzi with promising results in a murine model

    RSC Advances, Vol. 4, Núm. 110, pp. 65108-65120

  5. Triazolopyrimidine compounds containing first-row transition metals and their activity against the neglected infectious Chagas disease and leishmaniasis

    European Journal of Medicinal Chemistry, Vol. 85, pp. 526-534

2013

  1. In vitro activity of scorpiand-like azamacrocycle derivatives in promastigotes and intracellular amastigotes of Leishmania infantum and Leishmania braziliensis

    European Journal of Medicinal Chemistry, Vol. 62, pp. 466-477

  2. Scorpiand-like azamacrocycles prevent the chronic establishment of Trypanosoma cruzi in a murine model

    European Journal of Medicinal Chemistry, Vol. 70, pp. 189-198

2012

  1. In vitro and in vivo studies of the trypanocidal activity of four terpenoid derivatives against Trypanosoma cruzi

    American Journal of Tropical Medicine and Hygiene, Vol. 87, Núm. 3, pp. 481-488

  2. In vitro and in vivo trypanosomicidal activity of pyrazole-containing macrocyclic and macrobicyclic polyamines: Their action on acute and chronic phases of chagas disease

    Journal of Medicinal Chemistry, Vol. 55, Núm. 9, pp. 4231-4243

  3. In vitro anti-leishmania evaluation of nickel complexes with a triazolopyrimidine derivative against Leishmania infantum and Leishmania braziliensis

    Journal of Inorganic Biochemistry, Vol. 112, pp. 1-9

  4. In vitro evaluation of new terpenoid derivatives against Leishmania infantum and Leishmania Braziliensis

    Memorias do Instituto Oswaldo Cruz, Vol. 107, Núm. 3, pp. 370-376

  5. In vitro leishmanicidal activity of imidazole- or pyrazole-based benzo[g]phthalazine derivatives against leishmania infantum and leishmania braziliensis species

    Journal of Antimicrobial Chemotherapy, Vol. 67, Núm. 2, pp. 387-397

  6. Phthalazine derivatives containing imidazole rings behave as Fe-SOD inhibitors and show remarkable anti-T. cruzi activity in immunodeficient-mouse mode of infection

    Journal of Medicinal Chemistry, Vol. 55, Núm. 22, pp. 9900-9913