Publicaciones (66) Publicaciones de FRANCISCO CONEJERO LARA

2024

  1. Investigating vulnerability of the conserved SARS-CoV-2 spike's heptad repeat 2 as target for fusion inhibitors using chimeric miniproteins

    International Journal of Biological Macromolecules, Vol. 262

  2. Selective Formation of Pd-DNA Hybrids Using Tailored Palladium-Mediated Base Pairs: Towards Heteroleptic Pd-DNA Systems

    Angewandte Chemie - International Edition, Vol. 63, Núm. 11

2023

  1. Preparation and Investigation of Crucial Oligomers in the Early Stages of Aβ40 and Aβ42 Aggregation

    Methods in molecular biology (Clifton, N.J.), Vol. 2551, pp. 15-28

2022

  1. Conformational Stabilization of Gp41-Mimetic Miniproteins Opens Up New Ways of Inhibiting HIV-1 Fusion

    International Journal of Molecular Sciences, Vol. 23, Núm. 5

  2. Exploring Highly Conserved Regions of SARS-CoV-2 Spike S2 Subunit as Targets for Fusion Inhibition Using Chimeric Proteins

    International journal of molecular sciences, Vol. 23, Núm. 24

  3. Novel chimeric proteins mimicking SARS-CoV-2 spike epitopes with broad inhibitory activity

    International Journal of Biological Macromolecules, Vol. 222, pp. 2467-2478

2021

  1. Conformational flexibility of the conserved hydrophobic pocket of HIV-1 gp41. Implications for the discovery of small-molecule fusion inhibitors

    International Journal of Biological Macromolecules, Vol. 192, pp. 90-99

  2. Extremely thermostabilizing core mutations in coiled‐coil mimetic proteins of hiv‐1 gp41 produce diverse effects on target binding but do not affect their inhibitory activity

    Biomolecules, Vol. 11, Núm. 4

  3. In situ real-time monitoring of the mechanism of self-assembly of short peptide supramolecular polymers

    Materials Chemistry Frontiers, Vol. 5, Núm. 14, pp. 5452-5462

  4. Insights into the co-assemblies formed by different aromatic short-peptide amphiphiles

    Polymer Chemistry, Vol. 12, Núm. 47, pp. 6832-6845

  5. Insulin Crystals Grown in Short-Peptide Supramolecular Hydrogels Show Enhanced Thermal Stability and Slower Release Profile

    ACS Applied Materials and Interfaces, Vol. 13, Núm. 10, pp. 11672-11682

  6. Rapid conversion of amyloid-beta 1-40 oligomers to mature fibrils through a self-catalytic bimolecular process

    International Journal of Molecular Sciences, Vol. 22, Núm. 12

2020

  1. Molecular mechanisms of amyloid aggregation in human proteinopathies

    Protein Homeostasis Diseases: Mechanisms and Novel Therapies (Elsevier), pp. 153-179

  2. Probing Vulnerability of the gp41 C-Terminal Heptad Repeat as Target for Miniprotein HIV Inhibitors

    Journal of Molecular Biology, Vol. 432, Núm. 20, pp. 5577-5592

  3. Thermodynamic dissection of the interface between HIV-1 gp41 heptad repeats reveals cooperative interactions and allosteric effects

    Archives of Biochemistry and Biophysics, Vol. 688

2019

  1. Early mechanisms of amyloid fibril nucleation in model and disease-related proteins

    Biochimica et Biophysica Acta - Proteins and Proteomics, Vol. 1867, Núm. 11

  2. Structural and Thermodynamic Analysis of HIV-1 Fusion Inhibition Using Small gp41 Mimetic Proteins

    Journal of Molecular Biology, Vol. 431, Núm. 17, pp. 3091-3106

2018

  1. Dynamic micellar oligomers of amyloid beta peptides play a crucial role in their aggregation mechanisms

    Physical Chemistry Chemical Physics, Vol. 20, Núm. 31, pp. 20597-20614

  2. Global Protein Stabilization Does Not Suffice to Prevent Amyloid Fibril Formation

    ACS Chemical Biology, Vol. 13, Núm. 8, pp. 2094-2105

2017

  1. Sublingual priming with a HIV gp41-based subunit vaccine elicits mucosal antibodies and persistent B memory responses in non-human primates

    Frontiers in Immunology, Vol. 8, Núm. FEB