Publicaciones en colaboración con investigadores/as de University of Catania (9)

2023

  1. Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity

    Journal of Medicinal Chemistry, Vol. 66, Núm. 16, pp. 11447-11463

  2. Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain

    Journal of Medicinal Chemistry, Vol. 66, Núm. 14, pp. 9658-9683

  3. Synthesis, Computational Insights, and Evaluation of Novel Sigma Receptors Ligands

    ACS Chemical Neuroscience, Vol. 14, Núm. 10, pp. 1845-1858

2022

  1. Dual Sigma-1 receptor antagonists and hydrogen sulfide-releasing compounds for pain treatment: Design, synthesis, and pharmacological evaluation

    European Journal of Medicinal Chemistry, Vol. 230

  2. Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H3 and Sigma-1 Receptor Antagonists with Promising Antinociceptive Properties

    ACS Chemical Neuroscience, Vol. 13, Núm. 1, pp. 1-15

2020

  1. Novel N-Substituted Benzomorphan-Based Compounds: From MOR-Agonist/DOR-Antagonist to Biased/Unbiased MOR Agonists

    ACS Medicinal Chemistry Letters, Vol. 11, Núm. 5, pp. 678-685

2018

  1. (+)-Methyl (1 R, 2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] derivatives as potent and selective sigma receptor ligands: Stereochemistry and pharmacological properties

    Journal of Medicinal Chemistry, Vol. 61, Núm. 1, pp. 372-384

2017

  1. (+)-and (−)-Phenazocine enantiomers: Evaluation of their dual opioid agonist/σ1antagonist properties and antinociceptive effects

    European Journal of Medicinal Chemistry, Vol. 125, pp. 603-610

2011

  1. Novel potent and selective θ ligands: Evaluation of their agonist and antagonist properties

    Journal of Medicinal Chemistry, Vol. 54, Núm. 10, pp. 3669-3673