Publications (56) Publications de IRENE LUQUE FERNÁNDEZ

2024

  1. Monastrol suppresses invasion and metastasis in human colorectal cancer cells by targeting fascin independent of kinesin-Eg5 pathway

    Biomedicine and Pharmacotherapy, Vol. 175

2023

  1. A calorimetric and structural analysis of cooperativity in the thermal unfolding of the PDZ tandem of human Syntenin-1

    International Journal of Biological Macromolecules, Vol. 242

  2. Corrigendum to “A calorimetric and structural analysis of cooperativity in the thermal unfolding of the PDZ tandem of human Syntenin-1” [Int. J. Biol. Macromol. 242 (2023) 124662] (International Journal of Biological Macromolecules (2023) 242(P1), (S0141813023015568), (10.1016/j.ijbiomac.2023.124662))

    International Journal of Biological Macromolecules

2022

  1. Phage display identification of nanomolar ligands for human NEDD4-WW3: Energetic and dynamic implications for the development of broad-spectrum antivirals

    International Journal of Biological Macromolecules, Vol. 207, pp. 308-323

  2. Understanding binding affinity and specificity of modular protein domains: A focus in ligand design for the polyproline-binding families

    Advances in Protein Chemistry and Structural Biology (Academic Press Inc.), pp. 161-188

2021

  1. The fda‐approved antiviral raltegravir inhibits fascin1‐dependent invasion of colorectal tumor cells in vitro and in vivo

    Cancers, Vol. 13, Núm. 4, pp. 1-22

2020

  1. New role of the antidepressant imipramine as a Fascin1 inhibitor in colorectal cancer cells

    Experimental and Molecular Medicine, Vol. 52, Núm. 2, pp. 281-292

  2. Novel anti-invasive properties of a Fascin1 inhibitor on colorectal cancer cells

    Journal of Molecular Medicine, Vol. 98, Núm. 3, pp. 383-394

  3. Stability, conformational plasticity, oligomerization behaviour and equilibrium unfolding intermediates of the Ebola virus matrix protein VP40

    Journal of Biomolecular Structure and Dynamics

2019

  1. Binding site plasticity in viral PPxY Late domain recognition by the third WW domain of human NEDD4

    Scientific Reports, Vol. 9, Núm. 1

  2. Double Monoubiquitination Modifies the Molecular Recognition Properties of p15PAF Promoting Binding to the Reader Module of Dnmt1

    ACS Chemical Biology, Vol. 14, Núm. 10, pp. 2315-2326

  3. The p12 subunit of human polymerase uses an atypical PIP box for molecular recognition of proliferating cell nuclear antigen (PCNA)

    Journal of Biological Chemistry, Vol. 294, Núm. 11, pp. 3947-3956

  4. Ultrafast folding kinetics of WW domains reveal how the amino acid sequence determines the speed limit to protein folding

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, Núm. 17, pp. 8137-8142

2018

  1. Approaching the thermodynamic view of protein folding through the reproduction of Anfinsen's experiment by undergraduate physical biochemistry students

    Biochemistry and Molecular Biology Education, Vol. 46, Núm. 3, pp. 262-269

  2. Protein Folding Cooperativity and Thermodynamic Barriers of the Simplest β-Sheet Fold: A Survey of WW Domains

    Journal of Physical Chemistry B, Vol. 122, Núm. 49, pp. 11058-11071

2017

  1. Sublingual priming with a HIV gp41-based subunit vaccine elicits mucosal antibodies and persistent B memory responses in non-human primates

    Frontiers in Immunology, Vol. 8, Núm. FEB

2016

  1. A new physiological role for the DNA molecule as a protector against drying stress in desiccation-tolerant microorganisms

    Frontiers in Microbiology, Vol. 7, Núm. DEC

  2. From Binding-Induced Dynamic Effects in SH3 Structures to Evolutionary Conserved Sectors

    PLoS Computational Biology, Vol. 12, Núm. 5

2015

  1. Balancing the effect of corona on therapeutic efficacy and macrophage uptake of lipid nanocapsules

    Biomaterials, Vol. 61, pp. 266-278

  2. Crystal structure of the first WW domain of human YAP2 isoform

    Journal of Structural Biology, Vol. 191, Núm. 3, pp. 381-387