JOAQUÍN MARÍA
CAMPOS ROSA
Investigador desde 2023
OLGA MARÍA
CRUZ LÓPEZ
PROFESORA TITULAR DE UNIVERSIDAD
Publicaciones en las que colabora con OLGA MARÍA CRUZ LÓPEZ (22)
2023
2021
-
Design, synthesis, HER2 inhibition and anticancer evaluation of new substituted 1,5-dihydro-4,1-benzoxazepines
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 36, Núm. 1, pp. 1553-1563
-
Development of bozepinib-loaded nanocapsules for nose-to-brain delivery: Preclinical evaluation in glioblastoma
Nanomedicine, Vol. 16, Núm. 23, pp. 2095-2115
-
New insights into cytotoxic mechanisms of bozepinib against glioblastoma
European Journal of Pharmaceutical Sciences, Vol. 162
2018
-
The teaching team of experienced and beginner professors contributes to the continuous improvement of the teaching in the University of Granada
Edulearn 18. 10th International Conference on Education and New Learning Technology: (Palma, 2nd-4th of July, 2018). Conference proceedings
2017
-
1-(Benzenesulfonyl)-1,5-dihydro-4,1-benzoxazepine as a new scaffold for the design of antitumor compounds
Future Medicinal Chemistry, Vol. 9, Núm. 11, pp. 1129-1140
-
Synthesis of 1,4-benzoxathiin-9H-purine derivatives as antiproliferative agents
Targets in Heterocyclic Systems, Vol. 21, pp. 372-388
2014
-
HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib small compound
Oncotarget, Vol. 5, Núm. 11, pp. 3590-3606
2013
-
Bozepinib, a novel small antitumor agent, induces PKR-mediated apoptosis and synergizes with IFNα triggering apoptosis, autophagy and senescence
Drug Design, Development and Therapy, Vol. 7, pp. 1301-1313
2011
-
New (RS)-benzoxazepin-purines with antitumour activity: The chiral switch from (RS)-2,6-dichloro-9-[1-(p-nitrobenzenesulfonyl)-1,2,3,5-tetrahydro-4,1- benzoxazepin-3-yl]-9H-purine
European Journal of Medicinal Chemistry, Vol. 46, Núm. 1, pp. 249-258
-
Novel substituted quinazolines for potent EGFR tyrosine kinase inhibitors
Current Medicinal Chemistry, Vol. 18, Núm. 7, pp. 943-963
-
Syntheses of 2,3-dihydro-1,4-benzodioxins and bioisosteres as structural motifs for biologically active compounds
Current Organic Chemistry, Vol. 15, Núm. 6, pp. 869-887
2010
-
Neighboring-group participation involving the oxygen atom of the O,O- or O,N-acetal functional groups
Current Organic Chemistry, Vol. 14, Núm. 14, pp. 1461-1477
-
Synthesis of purine derivatives as scaffolds for a diversity of biological activities
Current Organic Chemistry, Vol. 14, Núm. 20, pp. 2463-2482
2009
-
Homochiral drugs: A demanding tendency of the pharmaceutical industry
Current Medicinal Chemistry, Vol. 16, Núm. 16, pp. 2064-2074
2008
-
Design, synthesis and anticancer activity against the MCF-7 cell line of benzo-fused 1,4-dihetero seven- and six-membered tethered pyrimidines and purines
Current Medicinal Chemistry, Vol. 15, Núm. 25, pp. 2614-2631
-
From 5-fluorouracil acyclonucleosides to benzo-fused six- and seven-membered rings linked to pyrimidine and purine bases: The shift from differentiating anticancer agents to apoptotic inducers
Expert Opinion on Drug Discovery, Vol. 3, Núm. 10, pp. 1223-1235
-
Synthesis and anticancer activity of (R,S)-9-(2,3-dihydro-1,4-benzoxathiin- 3-ylmethyl)-9H-purines
ChemMedChem, Vol. 3, Núm. 1, pp. 127-135
2007
-
1H and 13C NMR studies of 2-functionalized 5-(methylsulfonyl)-1-phenyl-1H-indoles
Magnetic Resonance in Chemistry, Vol. 45, Núm. 2, pp. 185-188
-
Design, syntheses, biological evaluation, and docking studies of 2-substituted 5-methylsulfonyl-1-phenyl-1H-indoles: Potent and selective in vitro cyclooxygenase-2 inhibitors
ChemMedChem, Vol. 2, Núm. 1, pp. 88-100