JAVIER
MURCIANO CALLES
PROFESOR TITULAR DE UNIVERSIDAD
JOSÉ CRISTÓBAL
MARTÍNEZ HERRERÍAS
PROFESOR TITULAR DE UNIVERSIDAD
Publikationen, an denen er mitarbeitet JOSÉ CRISTÓBAL MARTÍNEZ HERRERÍAS (16)
2023
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pH-Driven Polymorphic Behaviour of the Third PDZ Domain of PSD95: The Role of Electrostatic Interactions
Crystals, Vol. 13, Núm. 2
2022
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Phage display identification of nanomolar ligands for human NEDD4-WW3: Energetic and dynamic implications for the development of broad-spectrum antivirals
International Journal of Biological Macromolecules, Vol. 207, pp. 308-323
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Understanding binding affinity and specificity of modular protein domains: A focus in ligand design for the polyproline-binding families
Advances in Protein Chemistry and Structural Biology (Academic Press Inc.), pp. 161-188
2021
2020
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PDZ/PDZ interaction between PSD-95 and nNOS neuronal proteins: A thermodynamic analysis of the PSD95-PDZ2/nNOS-PDZ interaction
Journal of Molecular Recognition, Vol. 33, Núm. 4
2019
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Conformational changes in the third PDZ domain of the neuronal postsynaptic density protein 95
Acta Crystallographica Section D: Structural Biology, Vol. 75, pp. 381-391
2017
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Towards the improvement in stability of an anti-Aβ single-chain variable fragment, scFv-h3D6, as a way to enhance its therapeutic potential
Amyloid, Vol. 24, Núm. 3, pp. 167-175
2016
2014
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A thermodynamic study of the third PDZ domain of MAGUK neuronal protein PSD-95 reveals a complex three-state folding behavior
Biophysical Chemistry, Vol. 185, pp. 1-7
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Alteration of the C-terminal ligand specificity of the Erbin PDZ domain by allosteric mutational effects
Journal of Molecular Biology, Vol. 426, Núm. 21, pp. 3500-3508
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Post-translational modifications modulate ligand recognition by the third PDZ domain of the MAGUK protein PSD-95
PLoS ONE, Vol. 9, Núm. 2
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The impact of extra-domain structures and post-translational modifications in the folding/misfolding behaviour of the third PDZ domain of MAGUK neuronal protein PSD-95
PLoS ONE, Vol. 9, Núm. 5
2012
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The interconversion between a flexible β-sheet and a fibril β-arrangement constitutes the main conformational event during misfolding of PSD95-PDZ3 domain
Biophysical Journal, Vol. 103, Núm. 4, pp. 738-747
2011
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A comparative analysis of the folding and misfolding pathways of the third PDZ domain of PSD95 investigated under different pH conditions
Biophysical Chemistry, Vol. 158, Núm. 2-3, pp. 104-110
2010
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An oligomeric equilibrium intermediate as the precursory nucleus of globular and fibrillar supramacromolecular assemblies in a PDZ domain
Biophysical Journal, Vol. 99, Núm. 1, pp. 263-272
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Novel conformational aspects of the third PDZ domain of the neuronal post-synaptic density-95 protein revealed from two 1.4Å X-ray structures
Journal of Structural Biology, Vol. 170, Núm. 3, pp. 565-569