JAVIER
MURCIANO CALLES
PROFESOR TITULAR DE UNIVERSIDAD
California Institute of Technology
Pasadena, Estados UnidosPublicaciones en colaboración con investigadores/as de California Institute of Technology (6)
2017
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Directed evolution of an allosteric tryptophan synthase to create a platform for synthesis of noncanonical amino acids
Directed Enzyme Evolution: Advances and Applications (Springer International Publishing), pp. 1-16
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Unlocking Reactivity of TrpB: A General Biocatalytic Platform for Synthesis of Tryptophan Analogues
Journal of the American Chemical Society, Vol. 139, Núm. 31, pp. 10769-10776
2016
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A Panel of TrpB Biocatalysts Derived from Tryptophan Synthase through the Transfer of Mutations that Mimic Allosteric Activation
Angewandte Chemie - International Edition, Vol. 55, Núm. 38, pp. 11577-11581
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Common features in the unfolding and misfolding of PDZ domains and beyond: The modulatory effect of domain swapping and extra-elements
Scientific Reports, Vol. 6
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Tryptophan Synthase Uses an Atypical Mechanism To Achieve Substrate Specificity
Biochemistry, Vol. 55, Núm. 51, pp. 7043-7046
2015
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Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation
Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Núm. 47, pp. 14599-14604