Publicaciones (64) Publicaciones de JOSEFA LIBORIA SEGOVIA PARRA

2014

  1. Antitumoral alkylphospholipids alter cell lipid metabolism

    Anti-Cancer Agents in Medicinal Chemistry, Vol. 14, Núm. 4, pp. 545-558

2013

  1. Lipid Efflux Mediated by Alkylphospholipids in HepG2 Cells

    Cell Biochemistry and Biophysics, Vol. 66, Núm. 3, pp. 737-746

2012

  1. Design, synthesis, theoretical calculations and biological evaluation of new non-symmetrical choline kinase inhibitors

    European Journal of Medicinal Chemistry, Vol. 50, pp. 154-162

  2. La gracia de hoy

    Narcea

2011

  1. Antitumoral alkylphospholipids induce cholesterol efflux from the plasma membrane in HepG2 cells

    Journal of Pharmacology and Experimental Therapeutics, Vol. 336, Núm. 3, pp. 866-873

2010

  1. Alterations in the homeostasis of phospholipids and cholesterol by antitumor alkylphospholipids

    Lipids in Health and Disease, Vol. 9

  2. Disruption of cellular cholesterol transport and homeostasis as a novel mechanism of action of membrane-targeted alkylphospholipid analogues

    British Journal of Pharmacology, Vol. 160, Núm. 2, pp. 355-366

2009

  1. Hexadecylphosphocholine alters nonvesicular cholesterol traffic from the plasma membrane to the endoplasmic reticulum and inhibits the synthesis of sphingomyelin in HepG2 cells

    International Journal of Biochemistry and Cell Biology, Vol. 41, Núm. 6, pp. 1296-1303

2008

  1. Hexadecylphosphocholine interferes with the intracellular transport of cholesterol in HepG2 cells

    FEBS Journal, Vol. 275, Núm. 8, pp. 1675-1686

2007

  1. Effects of ethanol on the remodeling of neutral lipids and phospholipids in brain mitochondria and microsomes

    Neurochemistry International, Vol. 50, Núm. 6, pp. 858-865

2006

  1. Ethanol specifically alters the synthesis, acylation and transbilayer movement of aminophospholipids in rat-liver microsomes

    Life Sciences, Vol. 78, Núm. 24, pp. 2781-2786

  2. Hexadecylphosphocholine disrupts cholesterol homeostasis and induces the accumulation of free cholesterol in HepG2 tumour cells

    Biochemical Pharmacology, Vol. 71, Núm. 8, pp. 1114-1121

2004

  1. Hexadecylphosphocholine inhibits phosphatidylcholine synthesis via both the methylation of phosphatidylethanolamine and CDP-choline pathways in HepG2 cells

    International Journal of Biochemistry and Cell Biology, Vol. 36, Núm. 1, pp. 153-161

2002

  1. Comparative study of the effects of short- and long-term ethanol treatment and alcohol withdrawal on phospholipid biosynthesis in rat hepatocytes

    Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology, Vol. 131, Núm. 3, pp. 491-497

  2. Hexadecylphosphocholine inhibits phosphatidylcholine biosynthesis and the proliferation of HepG2 cells

    European Journal of Biochemistry, Vol. 269, Núm. 18, pp. 4649-4655

  3. Resistance of HepG2 cells against the adverse effects of ethanol related to neutral lipid and phospholipid metabolism

    Biochemical Pharmacology, Vol. 63, Núm. 8, pp. 1485-1490

2001

  1. Chronic ingestion of ethanol stimulates lipogenic response in rat hepatocytes

    Life Sciences, Vol. 68, Núm. 11, pp. 1295-1304

  2. Modulation of biosynthesis of phosphatidylcholine via CDP-choline in rat liver: Influence of ethanol on the microsomal cholinephosphotransferase activity

    Molecular and Cellular Biochemistry, Vol. 217, Núm. 1-2, pp. 43-50

1998

  1. Incorporation of exogenous precursors into neutral lipids and phospholipids in rat hepatocytes: Effect of ethanol in vitro

    Biochemical Pharmacology, Vol. 56, Núm. 12, pp. 1639-1644

1996

  1. Adaptive changes induced by chronic ethanol ingestion on hepatic mitochondrial and microsomal enzyme activities

    International Journal of Biochemistry and Cell Biology, Vol. 28, Núm. 1, pp. 23-27