Publicaciones en colaboración con investigadores/as de Università di Perugia (9)

2023

  1. New bioisosteric sulphur-containing choline kinase inhibitors with a tracked mode of action

    European journal of medicinal chemistry, Vol. 246, pp. 115003

2022

  1. Anticancer Activity of the Choline Kinase Inhibitor PL48 Is Due to Selective Disruption of Choline Metabolism and Transport Systems in Cancer Cell Lines

    Pharmaceutics, Vol. 14, Núm. 2

  2. Biological Evaluation of New Thienopyridinium and Thienopyrimidinium Derivatives as Human Choline Kinase Inhibitors

    Pharmaceutics, Vol. 14, Núm. 4

2021

  1. 3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine

    Nature Communications, Vol. 12, Núm. 1

2020

  1. Synthesis, biological evaluation, in silico modeling and crystallization of novel small monocationic molecules with potent antiproliferative activity by dual mechanism

    European Journal of Medicinal Chemistry, Vol. 207

  2. Targeting Aryl hydrocarbon receptor for next-generation immunotherapies: Selective modulators (SAhRMs) versus rapidly metabolized ligands (RMAhRLs)

    European Journal of Medicinal Chemistry, Vol. 185

2018

  1. Lead optimization-hit expansion of new asymmetrical pyridinium/quinolinium compounds as choline kinase α1 inhibitors

    Future Medicinal Chemistry, Vol. 10, Núm. 15, pp. 1769-1786

2015

  1. Pharmacophore-Based Virtual Screening to Discover New Active Compounds for Human Choline Kinase α1

    Molecular Informatics, Vol. 34, Núm. 6-7, pp. 458-466

2014

  1. Choline kinase active site provides features for designing versatile inhibitors

    Current Topics in Medicinal Chemistry, Vol. 14, Núm. 23, pp. 2684-2693