LUIS CARLOS
LÓPEZ GARCÍA
CATEDRÁTICO DE UNIVERSIDAD
DARÍO
ACUÑA CASTROVIEJO
Investigador desde null
Publicacións nas que colabora con DARÍO ACUÑA CASTROVIEJO (64)
2022
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Melatonin drives apoptosis in head and neck cancer by increasing mitochondrial ROS generated via reverse electron transport
Journal of Pineal Research, Vol. 73, Núm. 3
2021
2019
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β-RA reduces DMQ/CoQ ratio and rescues the encephalopathic phenotype in Coq9 R239X mice
EMBO Molecular Medicine, Vol. 11, Núm. 1
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Lack of NLRP3 Inflammasome Activation Reduces Age-Dependent Sarcopenia and Mitochondrial Dysfunction, Favoring the Prophylactic Effect of Melatonin
Journals of Gerontology - Series A Biological Sciences and Medical Sciences, Vol. 74, Núm. 11, pp. 1699-1708
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Melatonin enhances cisplatin and radiation cytotoxicity in head and neck squamous cell carcinoma by stimulating mitochondrial ROS generation, apoptosis, and autophagy
Oxidative Medicine and Cellular Longevity, Vol. 2019
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Rapamycin administration is not a valid therapeutic strategy for every case of mitochondrial disease
EBioMedicine, Vol. 42, pp. 511-523
2018
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Combination of melatonin and rapamycin for head and neck cancer therapy: Suppression of AKT/mTOR pathway activation, and activation of mitophagy and apoptosis via mitochondrial function regulation
Journal of Pineal Research, Vol. 64, Núm. 3
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In Vivo Determination of Mitochondrial Respiration in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Treated Zebrafish Reveals the Efficacy of Melatonin in Restoring Mitochondrial Normalcy
Zebrafish, Vol. 15, Núm. 1, pp. 15-26
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Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis
Scientific Reports, Vol. 8, Núm. 1
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The Protective Effect of Melatonin Against Age-Associated, Sarcopenia-Dependent Tubular Aggregate Formation, Lactate Depletion, and Mitochondrial Changes
Journals of Gerontology - Series A Biological Sciences and Medical Sciences, Vol. 73, Núm. 10, pp. 1330-1338
2017
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CoQ deficiency causes disruption of mitochondrial sulfide oxidation, a new pathomechanism associated with this syndrome
EMBO Molecular Medicine, Vol. 9, Núm. 1, pp. 78-95
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Melatonin administration to wild-type mice and nontreated NLRP3 mutant mice share similar inhibition of the inflammatory response during sepsis
Journal of Pineal Research, Vol. 63, Núm. 1
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Melatonin enhances neural stem cell differentiation and engraftment by increasing mitochondrial function
Journal of Pineal Research, Vol. 63, Núm. 2
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Melatonin protects rats from radiotherapyinduced small intestine toxicity
PLoS ONE, Vol. 12, Núm. 4
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Melatonin, clock genes and mitochondria in sepsis
Cellular and Molecular Life Sciences, Vol. 74, Núm. 21, pp. 3965-3987
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Mitochondrial impairment and melatonin protection in parkinsonian mice do not depend of inducible or neuronal nitric oxide synthases
PLoS ONE, Vol. 12, Núm. 8
2016
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Identification of morphological markers of sarcopenia at early stage of aging in skeletal muscle of mice
Experimental Gerontology, Vol. 83, pp. 22-30
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Melatonin rescues zebrafish embryos from the parkinsonian phenotype restoring the parkin/PINK1/DJ-1/MUL1 network
Journal of Pineal Research, pp. 96-107
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Permeabilized myocardial fibers as model to detect mitochondrial dysfunction during sepsis and melatonin effects without disruption of mitochondrial network
Mitochondrion, Vol. 27, pp. 56-63
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Preliminary evidence suggesting that nonmetallic and metallic nanoparticle devices protect against the effects of environmental electromagnetic radiation by reducing oxidative stress and inflammatory status
European Journal of Integrative Medicine, Vol. 8, Núm. 5, pp. 835-840