LUIS CARLOS
LÓPEZ GARCÍA
CATEDRÁTICO DE UNIVERSIDAD
GERMAINE
ESCAMES ROSA
CATEDRÁTICA DE UNIVERSIDAD
GERMAINE ESCAMES ROSA-rekin lankidetzan egindako argitalpenak (65)
2022
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Melatonin drives apoptosis in head and neck cancer by increasing mitochondrial ROS generated via reverse electron transport
Journal of Pineal Research, Vol. 73, Núm. 3
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The Q-junction and the inflammatory response are critical pathological and therapeutic factors in CoQ deficiency
Redox Biology, Vol. 55
2020
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Coenzyme Q10 modulates sulfide metabolism and links the mitochondrial respiratory chain to pathways associated to one carbon metabolism
Human Molecular Genetics, Vol. 29, Núm. 19, pp. 3296-3311
2019
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β-RA reduces DMQ/CoQ ratio and rescues the encephalopathic phenotype in Coq9 R239X mice
EMBO Molecular Medicine, Vol. 11, Núm. 1
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Lack of NLRP3 Inflammasome Activation Reduces Age-Dependent Sarcopenia and Mitochondrial Dysfunction, Favoring the Prophylactic Effect of Melatonin
Journals of Gerontology - Series A Biological Sciences and Medical Sciences, Vol. 74, Núm. 11, pp. 1699-1708
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Melatonin enhances cisplatin and radiation cytotoxicity in head and neck squamous cell carcinoma by stimulating mitochondrial ROS generation, apoptosis, and autophagy
Oxidative Medicine and Cellular Longevity, Vol. 2019
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Rapamycin administration is not a valid therapeutic strategy for every case of mitochondrial disease
EBioMedicine, Vol. 42, pp. 511-523
2018
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Combination of melatonin and rapamycin for head and neck cancer therapy: Suppression of AKT/mTOR pathway activation, and activation of mitophagy and apoptosis via mitochondrial function regulation
Journal of Pineal Research, Vol. 64, Núm. 3
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In Vivo Determination of Mitochondrial Respiration in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Treated Zebrafish Reveals the Efficacy of Melatonin in Restoring Mitochondrial Normalcy
Zebrafish, Vol. 15, Núm. 1, pp. 15-26
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Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis
Scientific Reports, Vol. 8, Núm. 1
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The Protective Effect of Melatonin Against Age-Associated, Sarcopenia-Dependent Tubular Aggregate Formation, Lactate Depletion, and Mitochondrial Changes
Journals of Gerontology - Series A Biological Sciences and Medical Sciences, Vol. 73, Núm. 10, pp. 1330-1338
2017
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CoQ deficiency causes disruption of mitochondrial sulfide oxidation, a new pathomechanism associated with this syndrome
EMBO Molecular Medicine, Vol. 9, Núm. 1, pp. 78-95
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Melatonin administration to wild-type mice and nontreated NLRP3 mutant mice share similar inhibition of the inflammatory response during sepsis
Journal of Pineal Research, Vol. 63, Núm. 1
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Melatonin enhances neural stem cell differentiation and engraftment by increasing mitochondrial function
Journal of Pineal Research, Vol. 63, Núm. 2
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Melatonin protects rats from radiotherapyinduced small intestine toxicity
PLoS ONE, Vol. 12, Núm. 4
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Melatonin, clock genes and mitochondria in sepsis
Cellular and Molecular Life Sciences, Vol. 74, Núm. 21, pp. 3965-3987
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Mitochondrial impairment and melatonin protection in parkinsonian mice do not depend of inducible or neuronal nitric oxide synthases
PLoS ONE, Vol. 12, Núm. 8
2016
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Identification of morphological markers of sarcopenia at early stage of aging in skeletal muscle of mice
Experimental Gerontology, Vol. 83, pp. 22-30
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Melatonin rescues zebrafish embryos from the parkinsonian phenotype restoring the parkin/PINK1/DJ-1/MUL1 network
Journal of Pineal Research, pp. 96-107
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Permeabilized myocardial fibers as model to detect mitochondrial dysfunction during sepsis and melatonin effects without disruption of mitochondrial network
Mitochondrion, Vol. 27, pp. 56-63