Publicaciones en las que colabora con ANA CONEJO GARCÍA (28)

2014

  1. Discovery of a new binding site on human choline kinase α1: Design, synthesis, crystallographic studies, and biological evaluation of asymmetrical bispyridinium derivatives

    Journal of Medicinal Chemistry, Vol. 57, Núm. 2, pp. 507-515

2013

  1. Antiproliferative activity, cell cycle, and apoptosis studies of a series of 6-substituted 9H-purin-9-yl-pyridinium derivatives on a human cervical carcinoma cell line

    ChemMedChem, Vol. 8, Núm. 8, pp. 1266-1269

  2. Chromatographic enantioresolution of six purine derivatives endowed with anti-human breast cancer activity

    Chromatographia, Vol. 76, Núm. 9-10, pp. 475-482

  3. Enantiospecific synthesis of heterocycles linked to purines: Different apoptosis modulation of enantiomers in breast cancer cells

    Current Medicinal Chemistry, Vol. 20, Núm. 38, pp. 4924-4934

2012

  1. 1H and 13C NMR spectral assignments of pyridinium salts linked to a N-9 or N-3 adenine moiety

    Magnetic Resonance in Chemistry, Vol. 50, Núm. 6, pp. 466-469

  2. Design, synthesis, theoretical calculations and biological evaluation of new non-symmetrical choline kinase inhibitors

    European Journal of Medicinal Chemistry, Vol. 50, pp. 154-162

  3. The selective cytotoxic activity in breast cancer cells by an anthranilic alcohol-derived acyclic 5-fluorouracil O,N-acetal is mediated by endoplasmic reticulum stress-induced apoptosis

    European Journal of Medicinal Chemistry, Vol. 50, pp. 376-382

2011

  1. Homodimeric bis-quaternary heterocyclic ammonium salts as potent acetyl- and butyrylcholinesterase inhibitors: A systematic investigation of the influence of linker and cationic heads over affinity and selectivity

    Journal of Medicinal Chemistry, Vol. 54, Núm. 8, pp. 2627-2645

  2. Synthesis and anticancer activity of (RS)-9-(2,3-dihydro-1,4- benzoxaheteroin-2-ylmethyl)-9H-purines

    European Journal of Medicinal Chemistry, Vol. 46, Núm. 9, pp. 3795-3801

2009

  1. Homochiral drugs: A demanding tendency of the pharmaceutical industry

    Current Medicinal Chemistry, Vol. 16, Núm. 16, pp. 2064-2074

2008

  1. Design, synthesis and anticancer activity against the MCF-7 cell line of benzo-fused 1,4-dihetero seven- and six-membered tethered pyrimidines and purines

    Current Medicinal Chemistry, Vol. 15, Núm. 25, pp. 2614-2631

  2. From 5-fluorouracil acyclonucleosides to benzo-fused six- and seven-membered rings linked to pyrimidine and purine bases: The shift from differentiating anticancer agents to apoptotic inducers

    Expert Opinion on Drug Discovery, Vol. 3, Núm. 10, pp. 1223-1235

  3. Latest advances on regiospecif ic microwave-assisted synthesis of novel purine derivatives as antitumor agents

    Expert Opinion on Therapeutic Patents, Vol. 18, Núm. 2, pp. 211-222

  4. Regiospecific microwave-assisted synthesis and cytotoxic activity against human breast cancer cells of (RS)-6-substituted-7- or 9-(2,3-dihydro-5H-1,4-benzodioxepin-3-yl)-7H- or -9H-purines

    European Journal of Medicinal Chemistry, Vol. 43, Núm. 8, pp. 1742-1748

  5. Synthesis and anticancer activity of (R,S)-9-(2,3-dihydro-1,4-benzoxathiin- 3-ylmethyl)-9H-purines

    ChemMedChem, Vol. 3, Núm. 1, pp. 127-135

2007

  1. Cyclophanes and bicyclophanes: Fascinating molecules in organic chemistry

    Targets in Heterocyclic Systems, Vol. 11, pp. 431-448

  2. QSAR as a tool for the development of potent antiproliferative agents by inhibition of choline kinase

    Current Computer-Aided Drug Design, Vol. 3, Núm. 4, pp. 297-313

2006

  1. (Q)SAR studies to design new human choline kinase inhibitors as antiproliferative drugs

    Current Medicinal Chemistry, Vol. 13, Núm. 11, pp. 1231-1248

  2. Characterization of latex-antineoplastic drug complexes by differential scanning calorimetry and microphotography

    Pharmazie, Vol. 61, Núm. 12, pp. 1009-1013

2005

  1. 1H and 13C spectral assignment of symmetrical bis[(4-aminosubstituted)quinolinium] derivatives

    Magnetic Resonance in Chemistry, Vol. 43, Núm. 12, pp. 1066-1071