Publications (140) Publications de MIGUEL ÁNGEL GALLO MEZO

2018

  1. Lead optimization-hit expansion of new asymmetrical pyridinium/quinolinium compounds as choline kinase α1 inhibitors

    Future Medicinal Chemistry, Vol. 10, Núm. 15, pp. 1769-1786

  2. Thiadiazoline- And pyrazoline-based carboxamides and carbothioamides: Synthesis and inhibition against nitric oxide synthase

    Journal of Chemistry, Vol. 2018

2016

  1. 1H and 13C NMR spectral assignment of N,N′-disubstituted thiourea and urea derivatives active against nitric oxide synthase

    Magnetic Resonance in Chemistry, pp. 793-799

  2. 1H and 13C NMR spectral assignments of 1,1′-(((ethane-1,2-diylbis(oxy))bis(4,1-phenylene))bis(methylene))-bispyridinium and -bisquinolinium bromide derivatives

    Magnetic Resonance in Chemistry

  3. Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1)

    Scientific Reports, Vol. 6

  4. N, N ′-Disubstituted thiourea and urea derivatives: Design, synthesis, docking studies and biological evaluation against nitric oxide synthase

    MedChemComm, Vol. 7, Núm. 4, pp. 667-678

  5. Quinazolinones, Quinazolinthiones, and Quinazolinimines as Nitric Oxide Synthase Inhibitors: Synthetic Study and Biological Evaluation

    Archiv der Pharmazie, pp. 638-650

  6. Synthesis of oxadiazoline and quinazolinone derivatives and their biological evaluation as nitric oxide synthase inhibitors

    Medicinal Chemistry Research, Vol. 25, Núm. 6, pp. 1260-1273

2015

  1. Amide-controlled, one-pot synthesis of tri-substituted purines generates structural diversity and analogues with trypanocidal activity

    Scientific Reports, Vol. 5

  2. Development of urea and thiourea kynurenamine derivatives: Synthesis, molecular modeling, and biological evaluation as nitric oxide synthase inhibitors

    ChemMedChem, Vol. 10, Núm. 5, pp. 874-882

  3. NMR assignments and structural characterization of new thiourea and urea kynurenamine derivatives nitric oxide synthase inhibitors

    Magnetic Resonance in Chemistry, Vol. 53, Núm. 12, pp. 1071-1079

  4. New more polar symmetrical bipyridinic compounds: New strategy for the inhibition of choline kinase α1

    Future Medicinal Chemistry, Vol. 7, Núm. 4, pp. 417-436

  5. New more polar symmetrical choline kinase inhibitors II: Study of setting up a new scaffold for the cancer therapy

    Journal of Biological Research (Italy)

  6. Pharmacophore-Based Virtual Screening to Discover New Active Compounds for Human Choline Kinase α1

    Molecular Informatics, Vol. 34, Núm. 6-7, pp. 458-466

  7. Synthesis of 6,8,9 poly-substituted purine analogue libraries as pro-apoptotic inducers of human leukemic lymphocytes and DAPK-1 inhibitors

    Organic and Biomolecular Chemistry, Vol. 13, Núm. 18, pp. 5224-5234

2014

  1. 1H, 13C NMR studies of new 3-aminophenol isomers linked to pyridinium salts

    Magnetic Resonance in Chemistry, Vol. 52, Núm. 1-2, pp. 40-46

  2. Discovery of a new binding site on human choline kinase α1: Design, synthesis, crystallographic studies, and biological evaluation of asymmetrical bispyridinium derivatives

    Journal of Medicinal Chemistry, Vol. 57, Núm. 2, pp. 507-515

2013

  1. Antiproliferative activity, cell cycle, and apoptosis studies of a series of 6-substituted 9H-purin-9-yl-pyridinium derivatives on a human cervical carcinoma cell line

    ChemMedChem, Vol. 8, Núm. 8, pp. 1266-1269

  2. Chromatographic enantioresolution of six purine derivatives endowed with anti-human breast cancer activity

    Chromatographia, Vol. 76, Núm. 9-10, pp. 475-482

  3. Enantiospecific synthesis of heterocycles linked to purines: Different apoptosis modulation of enantiomers in breast cancer cells

    Current Medicinal Chemistry, Vol. 20, Núm. 38, pp. 4924-4934