MARÍA DEL CARMEN
NÚÑEZ CARRETERO
Investigadora en el periodo 2009-2019
ANTONIO
ESPINOSA UBEDA
Investigador en el periodo 2002-2011
Publicaciones en las que colabora con ANTONIO ESPINOSA UBEDA (14)
2009
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Acyclonucleosides, modified seco-nucleosides, and salicyl- or catechol-derived acyclic 5-fluorouracil O,N-acetals: Antiproliferative activities, cellular differentiation and apoptosis
Current Medicinal Chemistry, Vol. 16, Núm. 9, pp. 1166-1183
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Homochiral drugs: A demanding tendency of the pharmaceutical industry
Current Medicinal Chemistry, Vol. 16, Núm. 16, pp. 2064-2074
2008
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Design, synthesis and anticancer activity against the MCF-7 cell line of benzo-fused 1,4-dihetero seven- and six-membered tethered pyrimidines and purines
Current Medicinal Chemistry, Vol. 15, Núm. 25, pp. 2614-2631
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Regiospecific microwave-assisted synthesis and cytotoxic activity against human breast cancer cells of (RS)-6-substituted-7- or 9-(2,3-dihydro-5H-1,4-benzodioxepin-3-yl)-7H- or -9H-purines
European Journal of Medicinal Chemistry, Vol. 43, Núm. 8, pp. 1742-1748
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Synthesis and anticancer activity of (R,S)-9-(2,3-dihydro-1,4-benzoxathiin- 3-ylmethyl)-9H-purines
ChemMedChem, Vol. 3, Núm. 1, pp. 127-135
2007
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6′-Chloro-7- or 9-(2,3-dihydro-5H-4,1-benzoxathiepin-3-yl)-7H- or 9H-purines and their corresponding sulfones as a new family of cytotoxic drugs
Tetrahedron, Vol. 63, Núm. 1, pp. 183-190
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A synthetic uracil derivative with antitumor activity through decreasing cyclin D1 and Cdk1, and increasing p21 and p27 in MCF-7 cells
Breast Cancer Research and Treatment, Vol. 105, Núm. 3, pp. 237-246
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QSAR as a tool for the development of potent antiproliferative agents by inhibition of choline kinase
Current Computer-Aided Drug Design, Vol. 3, Núm. 4, pp. 297-313
2006
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Synthesis and anticancer activity studies of novel 1-(2,3-dihydro-5H-1,4-benzodioxepin-3-yl)uracil and (6′-substituted)-7- or 9-(2,3-dihydro-5H-1,4-benzodioxepin-3-yl)-7H- or 9H-purines
Tetrahedron, Vol. 62, Núm. 50, pp. 11724-11733
2003
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Anticancer bisquaternary heterocyclic compounds: A ras-ional design
Farmaco, Vol. 58, Núm. 3, pp. 221-229
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QSAR-derived Choline Kinase inhibitors: How rational can antiproliferative drug design be?
Current Medicinal Chemistry, Vol. 10, Núm. 13, pp. 1095-1112
2002
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1H and 13C chemical shifts for bis(benzopyridinium) dibromides with semirigid aromatic linkers
Magnetic Resonance in Chemistry, Vol. 40, Núm. 8, pp. 554-556
2000
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QSAR of 1,1'-(1,2-ethylenebisbenzyl)bis(4-substitutedpyridinium) dibromides as choline kinase inhibitors: A different approach for antiproliferative drug design
Bioorganic and Medicinal Chemistry Letters, Vol. 10, Núm. 8, pp. 767-770
1997
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Choline kinase inhibitors as a novel approach for antiproliferative drug design
Oncogene, Vol. 15, Núm. 19, pp. 2289-2301