MARÍA PAZ
CARRASCO JIMÉNEZ
CATEDRÁTICA DE UNIVERSIDAD
PABLO
RÍOS MARCO
Researcher in the period 2013-2014
Publications by the researcher in collaboration with PABLO RÍOS MARCO (22)
2022
2021
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Anticancer and structure activity relationship of non-symmetrical choline kinase inhibitors
Pharmaceutics, Vol. 13, Núm. 9
2019
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Choline kinase inhibitors EB-3D and EB-3P interferes with lipid homeostasis in HepG2 cells
Scientific Reports, Vol. 9, Núm. 1
2018
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1,2-Diphenoxiethane salts as potent antiplasmodial agents
Bioorganic and Medicinal Chemistry Letters, Vol. 28, Núm. 14, pp. 2485-2489
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Lead optimization-hit expansion of new asymmetrical pyridinium/quinolinium compounds as choline kinase α1 inhibitors
Future Medicinal Chemistry, Vol. 10, Núm. 15, pp. 1769-1786
2017
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Alkylphospholipids: An update on molecular mechanisms and clinical relevance
Biochimica et Biophysica Acta - Biomembranes, Vol. 1859, Núm. 9, pp. 1657-1667
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Choline kinase inhibition and docking studies of a series of 6-(benzylthio)-9H-purin-9-yl-pyridinium derivatives
Medicinal Chemistry Research, Vol. 26, Núm. 11, pp. 2809-2815
2016
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Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1)
Scientific Reports, Vol. 6
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Pleiotropic effects of antitumour alkylphospholipids on cholesterol transport and metabolism
Experimental Cell Research, Vol. 340, Núm. 1, pp. 81-90
2015
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Cholesterol homeostasis and autophagic flux in perifosine-treated human hepatoblastoma HepG2 and glioblastoma U-87 MG cell lines
Biochemical Pharmacology, Vol. 96, Núm. 1, pp. 10-19
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New more polar symmetrical bipyridinic compounds: New strategy for the inhibition of choline kinase α1
Future Medicinal Chemistry, Vol. 7, Núm. 4, pp. 417-436
2014
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Antitumoral alkylphospholipids alter cell lipid metabolism
Anti-Cancer Agents in Medicinal Chemistry, Vol. 14, Núm. 4, pp. 545-558
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Choline kinase active site provides features for designing versatile inhibitors
Current Topics in Medicinal Chemistry, Vol. 14, Núm. 23, pp. 2684-2693
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Discovery of a new binding site on human choline kinase α1: Design, synthesis, crystallographic studies, and biological evaluation of asymmetrical bispyridinium derivatives
Journal of Medicinal Chemistry, Vol. 57, Núm. 2, pp. 507-515
2013
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Alkylphospholipids deregulate cholesterol metabolism and induce cell-cycle arrest and autophagy in U-87 MG glioblastoma cells
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, Vol. 1831, Núm. 8, pp. 1322-1334
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Lipid Efflux Mediated by Alkylphospholipids in HepG2 Cells
Cell Biochemistry and Biophysics, Vol. 66, Núm. 3, pp. 737-746
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New non-symmetrical choline kinase inhibitors
Bioorganic and Medicinal Chemistry, Vol. 21, Núm. 22, pp. 7146-7154
2012
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Design, synthesis, theoretical calculations and biological evaluation of new non-symmetrical choline kinase inhibitors
European Journal of Medicinal Chemistry, Vol. 50, pp. 154-162
2011
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Antitumoral alkylphospholipids induce cholesterol efflux from the plasma membrane in HepG2 cells
Journal of Pharmacology and Experimental Therapeutics, Vol. 336, Núm. 3, pp. 866-873
2010
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Alterations in the homeostasis of phospholipids and cholesterol by antitumor alkylphospholipids
Lipids in Health and Disease, Vol. 9