MARÍA PAZ
CARRASCO JIMÉNEZ
CATEDRÁTICA DE UNIVERSIDAD
LUISA CARLOTA
LÓPEZ CARA
PROFESORA TITULAR DE UNIVERSIDAD
Publications by the researcher in collaboration with LUISA CARLOTA LÓPEZ CARA (14)
2023
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New bioisosteric sulphur-containing choline kinase inhibitors with a tracked mode of action
European journal of medicinal chemistry, Vol. 246, pp. 115003
2022
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Anticancer Activity of the Choline Kinase Inhibitor PL48 Is Due to Selective Disruption of Choline Metabolism and Transport Systems in Cancer Cell Lines
Pharmaceutics, Vol. 14, Núm. 2
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Biological Evaluation of New Thienopyridinium and Thienopyrimidinium Derivatives as Human Choline Kinase Inhibitors
Pharmaceutics, Vol. 14, Núm. 4
2021
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Anticancer and structure activity relationship of non-symmetrical choline kinase inhibitors
Pharmaceutics, Vol. 13, Núm. 9
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New compounds with bioisosteric replacement of classic choline kinase inhibitors show potent antiplasmodial activity
Pharmaceutics, Vol. 13, Núm. 11
2020
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Synthesis, biological evaluation, in silico modeling and crystallization of novel small monocationic molecules with potent antiproliferative activity by dual mechanism
European Journal of Medicinal Chemistry, Vol. 207
2019
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Biomimetic magnetic nanocarriers drive choline kinase alpha inhibitor inside cancer cells for combined chemo-hyperthermia therapy
Pharmaceutics, Vol. 11, Núm. 8
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Choline kinase inhibitors EB-3D and EB-3P interferes with lipid homeostasis in HepG2 cells
Scientific Reports, Vol. 9, Núm. 1
2018
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1,2-Diphenoxiethane salts as potent antiplasmodial agents
Bioorganic and Medicinal Chemistry Letters, Vol. 28, Núm. 14, pp. 2485-2489
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Lead optimization-hit expansion of new asymmetrical pyridinium/quinolinium compounds as choline kinase α1 inhibitors
Future Medicinal Chemistry, Vol. 10, Núm. 15, pp. 1769-1786
2016
2015
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New more polar symmetrical bipyridinic compounds: New strategy for the inhibition of choline kinase α1
Future Medicinal Chemistry, Vol. 7, Núm. 4, pp. 417-436
2014
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Choline kinase active site provides features for designing versatile inhibitors
Current Topics in Medicinal Chemistry, Vol. 14, Núm. 23, pp. 2684-2693
2013
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New non-symmetrical choline kinase inhibitors
Bioorganic and Medicinal Chemistry, Vol. 21, Núm. 22, pp. 7146-7154