MANUEL
SÁNCHEZ MORENO
Investigador en el periodo 2021-2022
Universitat de València
Valencia, EspañaPublicaciones en colaboración con investigadores/as de Universitat de València (11)
2021
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Heterocyclic Diamines with Leishmanicidal Activity
ACS Infectious Diseases, Vol. 7, Núm. 12, pp. 3168-3181
2020
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Repositioning of leishmanicidal [1,2,3]Triazolo[1,5-a]pyridinium salts for Chagas disease treatment: Trypanosoma cruzi cell death involving mitochondrial membrane depolarisation and Fe-SOD inhibition
Parasitology Research, Vol. 119, Núm. 9, pp. 2943-2954
2019
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New polyamine drugs as more effective antichagas agents than benznidazole in both the acute and chronic phases
European Journal of Medicinal Chemistry, Vol. 164, pp. 27-46
2017
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Simple dialkyl pyrazole-3,5-dicarboxylates show in vitro and in vivo activity against disease-causing trypanosomatids
Parasitology, Vol. 144, Núm. 9, pp. 1133-1143
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Synthesis and in vitro leishmanicidal activity of novel [1,2,3]triazolo[1,5-a]pyridine salts
RSC Advances, Vol. 7, Núm. 26, pp. 15715-15726
2016
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In vitro antileishmanial activity of aza-scorpiand macrocycles. Inhibition of the antioxidant enzyme iron superoxide dismutase
RSC Advances, Vol. 6, Núm. 21, pp. 17446-17455
2014
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In vitro leishmanicidal activity of pyrazole-containing polyamine macrocycles which inhibit the Fe-SOD enzyme of Leishmania infantum and Leishmania braziliensis species
Parasitology, Vol. 141, Núm. 8, pp. 1031-1043
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Synthetic single and double aza-scorpiand macrocycles acting as inhibitors of the antioxidant enzymes iron superoxide dismutase and trypanothione reductase in Trypanosoma cruzi with promising results in a murine model
RSC Advances, Vol. 4, Núm. 110, pp. 65108-65120
2013
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In vitro activity of scorpiand-like azamacrocycle derivatives in promastigotes and intracellular amastigotes of Leishmania infantum and Leishmania braziliensis
European Journal of Medicinal Chemistry, Vol. 62, pp. 466-477
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Scorpiand-like azamacrocycles prevent the chronic establishment of Trypanosoma cruzi in a murine model
European Journal of Medicinal Chemistry, Vol. 70, pp. 189-198
2012
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In vitro and in vivo trypanosomicidal activity of pyrazole-containing macrocyclic and macrobicyclic polyamines: Their action on acute and chronic phases of chagas disease
Journal of Medicinal Chemistry, Vol. 55, Núm. 9, pp. 4231-4243