NATALIA AFRICA
NAVAS IGLESIAS
CATEDRÁTICA DE UNIVERSIDAD
José
Cabeza Barrera
Publications by the researcher in collaboration with José Cabeza Barrera (27)
2024
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Comprehensive Analysis of Cetuximab Critical Quality Attributes: Impact of Handling on Antigen-Antibody Binding
Pharmaceutics, Vol. 16, Núm. 9
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Comprehensive physicochemical and functional analysis of pembrolizumab based on controlled degradation studies: Impact on antigen–antibody binding
European Journal of Pharmaceutics and Biopharmaceutics, Vol. 194, pp. 131-147
2023
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Analysing the In-Use Stability of mRNA-LNP COVID-19 Vaccines Comirnaty™ (Pfizer) and Spikevax™ (Moderna): A Comparative Study of the Particulate
Vaccines, Vol. 11, Núm. 11
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Comprehensive physicochemical characterization of a peptide-based medicine: Teduglutide (Revestive®) structural description and stress testing
European Journal of Pharmaceutics and Biopharmaceutics, Vol. 184, pp. 103-115
2022
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Combined use of UV and MS data for ICH Stability-Indication Method: Quantification and isoforms identification of intact nivolumab
Microchemical Journal, Vol. 182
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Comprehensive Analysis of Nivolumab, A Therapeutic Anti-Pd-1 Monoclonal Antibody: Impact of Handling and Stress
Pharmaceutics, Vol. 14, Núm. 4
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Degradation and in-use stability study of five marketed therapeutic monoclonal antibodies by generic weak cation exchange liquid chromatographic method ((WCX)HPLC/DAD)
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, Vol. 1203
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Method for identification and quantification of intact teduglutide peptide using (RP)UHPLC-UV-(HESI/ORBITRAP)MS
Analytical Methods, Vol. 14, Núm. 43, pp. 4359-4369
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Tracking the physicochemical stability of teduglutide (Revestive®) clinical solutions over time in different storage containers
Journal of Pharmaceutical and Biomedical Analysis, Vol. 221
2021
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Stability study over time of clinical solutions of ziv-aflibercept prepared in infusion bags using a proper combination of physicochemical and functional strategies
Journal of Pharmaceutical and Biomedical Analysis, Vol. 203
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The relevance of monoclonal antibodies in the treatment of COVID-19
Vaccines, Vol. 9, Núm. 6
2020
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Comprehensive biophysical and functional study of ziv-aflibercept: characterization and forced degradation
Scientific Reports, Vol. 10, Núm. 1
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Intact charge variant analysis of ziv-aflibercept by cationic exchange liquid chromatography as a proof of concept: Comparison between volatile and non-volatile salts in the mobile phase
Journal of Pharmaceutical and Biomedical Analysis, Vol. 185
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Use of subcutaneous tocilizumab to prepare intravenous solutions for COVID-19 emergency shortage: Comparative analytical study of physicochemical quality attributes
Journal of Pharmaceutical Analysis, Vol. 10, Núm. 6, pp. 532-545
2019
2018
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Study of aggregation in therapeutic monoclonal antibodies subjected to stress and long-term stability tests by analyzing size exclusion liquid chromatographic profiles
International Journal of Biological Macromolecules, Vol. 118, pp. 511-524
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Validated reverse phase HPLC diode array method for the quantification of intact bevacizumab, infliximab and trastuzumab for long-term stability study
International Journal of Biological Macromolecules, Vol. 116, pp. 993-1003
2016
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Development and use of specific ELISA methods for quantifying the biological activity of bevacizumab, cetuximab and trastuzumab in stability studies
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, Vol. 1032, pp. 155-164
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Study and ICH validation of a reverse-phase liquid chromatographic method for the quantification of the intact monoclonal antibody cetuximab
Journal of Pharmaceutical Analysis, Vol. 6, Núm. 2, pp. 117-124
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The Effects of Light-Accelerated Degradation on the Aggregation of Marketed Therapeutic Monoclonal Antibodies Evaluated by Size-Exclusion Chromatography with Diode Array Detection
Journal of Pharmaceutical Sciences, Vol. 105, Núm. 4, pp. 1405-1418