Publikationen in Zusammenarbeit mit Forschern von University of Ferrara (28)

2015

  1. Synthesis and biological evaluation of a new series of 2-amino-3-aroyl thiophene derivatives as agonist allosteric modulators of the A1 adenosine receptor. A position-dependent effect study

    European Journal of Medicinal Chemistry, Vol. 101, pp. 185-204

2014

  1. Synthesis and biological evaluation of novel 2-amino-3-aroyl-4-neopentyl-5- substituted thiophene derivatives as allosteric enhancers of the A1 adenosine receptor

    Bioorganic and Medicinal Chemistry, Vol. 22, Núm. 1, pp. 148-166

  2. Synthesis and biological evaluation of novel allosteric enhancers of the A1adenosine receptor based on 2-amino-3-(4′-chlorobenzoyl)-4-substituted-5-arylethynyl thiophene

    Journal of Medicinal Chemistry, Vol. 57, Núm. 18, pp. 7673-7686

2012

  1. Design, synthesis and biological evaluation of hybrid molecules containing conjugated styryl ketone and α-bromoacryloyl moieties

    Letters in Drug Design and Discovery, Vol. 9, Núm. 2, pp. 140-152

  2. Structure-activity relationships of 2-amino-3-aroyl-4-[(4-arylpiperazin-1- yl)methyl]thiophenes. Part 2: Probing the influence of diverse substituents at the phenyl of the arylpiperazine moiety on allosteric enhancer activity at the A 1 adenosine receptor

    Bioorganic and Medicinal Chemistry, Vol. 20, Núm. 2, pp. 996-1007

  3. Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[(4- arylpiperazin-1-yl)methyl]-5-substituted-thiophenes. Effect of the 5-modification on allosteric enhancer activity at the A1 adenosine receptor

    Journal of Medicinal Chemistry, Vol. 55, Núm. 17, pp. 7719-7735

2011

  1. Synthesis and Antitumor Molecular Mechanism of Agents Based on Amino 2-(3',4',5'-Trimethoxybenzoyl)benzo[b]furan: Inhibition of Tubulin and Induction of Apoptosis

    ChemMedChem, Vol. 6, Núm. 10, pp. 1841-1853

  2. Synthesis of novel antimitotic agents based on 2-amino-3-aroyl-5-(hetero) arylethynyl thiophene derivatives

    Bioorganic and Medicinal Chemistry Letters

2010

  1. Substituted 2-(3′,4′,5′-trimethoxybenzoyl)-benzo[b] thiophene derivatives as potent tubulin polymerization inhibitors

    Bioorganic and Medicinal Chemistry, Vol. 18, Núm. 14, pp. 5114-5122

  2. Symmetrical α-bromoacryloylamido diaryldienone derivatives as a novel series of antiproliferative agents. Design, synthesis and biological evaluation

    Bioorganic and Medicinal Chemistry Letters, Vol. 20, Núm. 9, pp. 2733-2739

  3. Synthesis and antitumor activity of 1,5-disubstituted 1,2,4-triazoles as cis-restricted combretastatin analogues

    Journal of Medicinal Chemistry, Vol. 53, Núm. 10, pp. 4248-4258

  4. Synthesis and cellular pharmacology studies of a series of 2-amino-3-aroyl-4-substituted thiophene derivatives

    Medicinal Chemistry, Vol. 6, Núm. 6, pp. 329-343

2009

  1. 2-Arylamino-4-amino-5-aroylthiazoles. "One-pot" synthesis and biological evaluation of a new class of inhibitors of tubulin polymerization

    Journal of Medicinal Chemistry, Vol. 52, Núm. 17, pp. 5551-5555

  2. Design, synthesis and structure-activity relationship of 2-(3′,4′,5′-trimethoxybenzoyl)-benzo[b]furan derivatives as a novel class of inhibitors of tubulin polymerization

    Bioorganic and Medicinal Chemistry, Vol. 17, Núm. 19, pp. 6862-6871

  3. Discovery of 8-methoxypyrazino[1,2-a]indole as a new potent antiproliferative agent against human leukemia K562 cells. A structure-activity relationship study

    Letters in Drug Design and Discovery, Vol. 6, Núm. 4, pp. 298-303

  4. Hybrid α-bromoacryloylamido chalcones. Design, synthesis and biological evaluation

    Bioorganic and Medicinal Chemistry Letters, Vol. 19, Núm. 7, pp. 2022-2028

  5. α-bromoacrylamido N-substituted isatin derivatives as potent inducers of apoptosis in human myeloid leukemia cells

    ChemMedChem, Vol. 4, Núm. 10, pp. 1668-1676

  6. α-halogenoacrylic derivatives of antitumor agents

    Mini-Reviews in Medicinal Chemistry, Vol. 9, Núm. 1, pp. 81-94

2008

  1. Design, synthesis, and biological evaluation of thiophene analogues of chalcones

    Bioorganic and Medicinal Chemistry, Vol. 16, Núm. 10, pp. 5367-5376

  2. Synthesis and biological evaluation of 1-methyl-2-(3′,4′, 5′-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors

    Journal of Medicinal Chemistry, Vol. 51, Núm. 5, pp. 1464-1468