PEDRO JOSÉ
REAL LUNA
PROFESOR TITULAR DE UNIVERSIDAD
Columbia University
Nueva York, Estados UnidosPublications en collaboration avec des chercheurs de Columbia University (9)
2010
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The TLX1 oncogene drives aneuploidy in T cell transformation
Nature Medicine, Vol. 16, Núm. 11, pp. 1321-1327
2009
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NOTCH inhibition and glucocorticoid therapy in T-cell acute lymphoblastic leukemia
Leukemia, Vol. 23, Núm. 8, pp. 1374-1377
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WT1 mutations in T-ALL
Blood, Vol. 114, Núm. 5, pp. 1038-1045
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γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia
Nature Medicine, Vol. 15, Núm. 1, pp. 50-58
2008
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NOTCH1 extracellular juxtamembrane expansion mutations in T-ALL
Blood, Vol. 112, Núm. 3, pp. 733-740
2007
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Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia
Nature Medicine, Vol. 13, Núm. 10, pp. 1203-1210
2006
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A novel role for proline- and acid-rich basic region leucine zipper (PAR bZIP) proteins in the transcriptional regulation of a BH3-only proapoptotic gene
Journal of Biological Chemistry, Vol. 281, Núm. 50, pp. 38351-38357
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CUTLL1, a novel human T-cell lymphoma cell line with t(7;9) rearrangement, aberrant NOTCH1 activation and high sensitivity to γ-secretase inhibitors
Leukemia, Vol. 20, Núm. 7, pp. 1279-1287
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NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth
Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Núm. 48, pp. 18261-18266