ROGELIO JESÚS
PALOMINO MORALES

PROFESOR TITULAR DE UNIVERSIDAD

Foto de ROGELIO JESÚS

Foto de Hospital Universitario de Canarias

Hospital Universitario de Canarias

San Cristóbal de La Laguna, España

Publicaciones en colaboración con investigadores/as de Hospital Universitario de Canarias (7)

2022

Allosteric Communication in the Multifunctional and Redox NQO1 Protein Studied by Cavity‐Making Mutations
Antioxidants, Vol. 11, Núm. 6
Different phenotypic outcome due to site-specific phosphorylation in the cancer-associated NQO1 enzyme studied by phosphomimetic mutations
Archives of Biochemistry and Biophysics, Vol. 729
Targeting HIF-1α Function in Cancer through the Chaperone Action of NQO1: Implications of Genetic Diversity of NQO1
Journal of Personalized Medicine, Vol. 12, Núm. 5

2021

Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue
Redox Biology, Vol. 46

2017

Enhanced vulnerability of human proteins towards disease-associated inactivation through divergent evolution
Human Molecular Genetics, Vol. 26, Núm. 18, pp. 3531-3544
Site-to-site interdomain communication may mediate different loss-of-function mechanisms in a cancer-associated NQO1 polymorphism
Scientific Reports, Vol. 7

2016

Conformational dynamics is key to understanding loss-of-function of NQO1 cancer-associated polymorphisms and its correction by pharmacological ligands
Scientific Reports, Vol. 6