JOSÉ MANUEL
SÁNCHEZ RUIZ
CATEDRÁTICO DE UNIVERSIDAD
Georgia Institute of Technology
Atlanta, Estados UnidosPublicacions en col·laboració amb investigadors/es de Georgia Institute of Technology (8)
2017
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De novo active sites for resurrected Precambrian enzymes
Nature Communications, Vol. 8
2016
2015
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Mutational studies on resurrected ancestral proteins reveal conservation of site-specific amino acid preferences throughout evolutionary history
Molecular Biology and Evolution, Vol. 32, Núm. 2, pp. 440-455
2014
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Phenotypic comparisons of consensus variants versus laboratory resurrections of Precambrian proteins
Proteins: Structure, Function and Bioinformatics, Vol. 82, Núm. 6, pp. 887-896
2013
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Conservation of protein structure over four billion years
Structure, Vol. 21, Núm. 9, pp. 1690-1697
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Hyperstability and substrate promiscuity in laboratory resurrections of precambrian β-lactamases
Journal of the American Chemical Society, Vol. 135, Núm. 8, pp. 2899-2902
2011
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Single-molecule paleoenzymology probes the chemistry of resurrected enzymes
Nature Structural and Molecular Biology, Vol. 18, Núm. 5, pp. 592-596
2009
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Diversity of chemical mechanisms in thioredoxin catalysis revealed by single-molecule force spectroscopy
Nature Structural and Molecular Biology, Vol. 16, Núm. 8, pp. 890-896