Publicaciones (20) Publicaciones de AGUSTÍN HIDALGO GUTIÉRREZ

2024

  1. Early heart and skeletal muscle mitochondrial response to a moderate hypobaric hypoxia environment

    Journal of Physiology

  2. Oral β-RA induces metabolic rewiring leading to the rescue of diet-induced obesity

    Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1870, Núm. 7

2022

  1. Mechanisms and Therapeutic Effects of Benzoquinone Ring Analogs in Primary CoQ Deficiencies

    Antioxidants, Vol. 11, Núm. 4

  2. Melatonin drives apoptosis in head and neck cancer by increasing mitochondrial ROS generated via reverse electron transport

    Journal of Pineal Research, Vol. 73, Núm. 3

  3. The Q-junction and the inflammatory response are critical pathological and therapeutic factors in CoQ deficiency

    Redox Biology, Vol. 55

2021

  1. Animal models of coenzyme q deficiency: Mechanistic and translational learnings

    Antioxidants, Vol. 10, Núm. 11

  2. Metabolic targets of coenzyme q10 in mitochondria

    Antioxidants, Vol. 10, Núm. 4

  3. β-RA Targets Mitochondrial Metabolism and Adipogenesis, Leading to Therapeutic Benefits against CoQ Deficiency and Age-Related Overweight

    Biomedicines, Vol. 9, Núm. 10

2020

  1. Coenzyme Q10 modulates sulfide metabolism and links the mitochondrial respiratory chain to pathways associated to one carbon metabolism

    Human Molecular Genetics, Vol. 29, Núm. 19, pp. 3296-3311

2019

  1. β-RA reduces DMQ/CoQ ratio and rescues the encephalopathic phenotype in Coq9 R239X mice

    EMBO Molecular Medicine, Vol. 11, Núm. 1

  2. Hydroxytyrosol influences exercise-induced mitochondrial respiratory complex assembly into supercomplexes in rats

    Free Radical Biology and Medicine, Vol. 134, pp. 304-310

  3. Rapamycin administration is not a valid therapeutic strategy for every case of mitochondrial disease

    EBioMedicine, Vol. 42, pp. 511-523

2018

  1. CoQ10 supplementation rescues nephrotic syndrome through normalization of H2S oxidation pathway

    Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1864, Núm. 11, pp. 3708-3722

  2. In Vivo Determination of Mitochondrial Respiration in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Treated Zebrafish Reveals the Efficacy of Melatonin in Restoring Mitochondrial Normalcy

    Zebrafish, Vol. 15, Núm. 1, pp. 15-26

  3. Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis

    Scientific Reports, Vol. 8, Núm. 1

2017

  1. Antioxidant effect of exercise: Exploring the role of the mitochondrial complex I superassembly

    Redox Biology, Vol. 13, pp. 477-481

  2. CoQ deficiency causes disruption of mitochondrial sulfide oxidation, a new pathomechanism associated with this syndrome

    EMBO Molecular Medicine, Vol. 9, Núm. 1, pp. 78-95

  3. Melatonin administration to wild-type mice and nontreated NLRP3 mutant mice share similar inhibition of the inflammatory response during sepsis

    Journal of Pineal Research, Vol. 63, Núm. 1

  4. The role of sulfide oxidation impairment in the pathogenesis of primary CoQ deficiency

    Frontiers in Physiology

2016

  1. Gene therapy corrects mitochondrial dysfunction in hematopoietic progenitor cells and fibroblasts from Coq9R239X mice

    PLoS ONE, Vol. 11, Núm. 6