Publications (23) MERIEM CHAYAH GHADDAB publications

2024

  1. Synthesis and Anti-Diabetic Activity of an 8-Purine Derivative as a Novel DPP-4 Inhibitor in Obese Diabetic Zücker Rats

    Drug Design, Development and Therapy, Vol. 18, pp. 1133-1141

2022

  1. Melatonin induces fat browning by transdifferentiation of white adipocytes and de novo differentiation of mesenchymal stem cells

    Food and Function, Vol. 13, Núm. 6, pp. 3760-3775

2020

  1. Melatonin improves mitochondrial dynamics and function in the kidney of zücker diabetic fatty rats

    Journal of Clinical Medicine, Vol. 9, Núm. 9, pp. 1-14

  2. Time-restricted feeding improves body weight gain, lipid profiles, and atherogenic indices in cafeteria-diet-fed rats: Role of browning of inguinal white adipose tissue

    Nutrients, Vol. 12, Núm. 8, pp. 1-17

2019

  1. Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2- d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors

    Journal of Medicinal Chemistry, Vol. 62, Núm. 3, pp. 1274-1290

2018

  1. Thiadiazoline- And pyrazoline-based carboxamides and carbothioamides: Synthesis and inhibition against nitric oxide synthase

    Journal of Chemistry, Vol. 2018

2017

  1. Empleo de la plataforma reaxys como una herramienta útil para los estudiantes de química orgánica

    Evaluación de la Calidad de la Investigación y de la Educación Superior: libro de resúmenes XIV FECIES

  2. Fomento del trabajo colaborativo de los estudiantes de química farmacéutica mediante el uso de una wiki

    Evaluación de la Calidad de la Investigación y de la Educación Superior: libro de resúmenes XIV FECIES

  3. Uso de la base de datos reaxys en el área de la química farmacéutica para promover el aprendizaje del alumnado

    Evaluación de la Calidad de la Investigación y de la Educación Superior: libro de resúmenes XIV FECIES

  4. Uso de una wiki para fomentar el trabajo en grupo en química orgánica

    Evaluación de la Calidad de la Investigación y de la Educación Superior: libro de resúmenes XIV FECIES

2016

  1. 1H and 13C NMR spectral assignment of N,N′-disubstituted thiourea and urea derivatives active against nitric oxide synthase

    Magnetic Resonance in Chemistry, pp. 793-799

  2. N, N ′-Disubstituted thiourea and urea derivatives: Design, synthesis, docking studies and biological evaluation against nitric oxide synthase

    MedChemComm, Vol. 7, Núm. 4, pp. 667-678

  3. Quinazolinones, Quinazolinthiones, and Quinazolinimines as Nitric Oxide Synthase Inhibitors: Synthetic Study and Biological Evaluation

    Archiv der Pharmazie, pp. 638-650

  4. Synthesis of oxadiazoline and quinazolinone derivatives and their biological evaluation as nitric oxide synthase inhibitors

    Medicinal Chemistry Research, Vol. 25, Núm. 6, pp. 1260-1273

  5. Synthetic methodologies for the preparation of arginine-proline derivatives

    Current Bioactive Compounds, Vol. 12, Núm. 3, pp. 182-190

  6. The use of wiki to promote students’ learning in higher education (Degree in Pharmacy)

    International Journal of Educational Technology in Higher Education, Núm. 13

2015

  1. Development of urea and thiourea kynurenamine derivatives: Synthesis, molecular modeling, and biological evaluation as nitric oxide synthase inhibitors

    ChemMedChem, Vol. 10, Núm. 5, pp. 874-882

  2. NMR assignments and structural characterization of new thiourea and urea kynurenamine derivatives nitric oxide synthase inhibitors

    Magnetic Resonance in Chemistry, Vol. 53, Núm. 12, pp. 1071-1079

2014

  1. Design, synthesis and biological evaluation of arylcinnamide hybrid derivatives as novel anticancer agents

    European Journal of Medicinal Chemistry, Vol. 81, pp. 394-407

2013

  1. Synthesis and biological evaluation of 4,5-dihydro-1H-pyrazole derivatives as potential nNOS/iNOS selective inhibitors. Part 2: Influence of diverse substituents in both the phenyl moiety and the acyl group

    Bioorganic and Medicinal Chemistry, Vol. 21, Núm. 14, pp. 4132-4142