Publicaciones (24) Publicaciones de FRANCISCO ANGEL PÉREZ LARA

2023

  1. Intrinsic Disorder of the Neuronal SNARE Protein SNAP25a in its Pre-fusion Conformation

    Journal of Molecular Biology, Vol. 435, Núm. 10

2022

  1. Forces, Kinetics, and Fusion Efficiency Altered by the Full-Length Synaptotagmin-1 -PI(4,5)P2Interaction in Constrained Geometries

    Nano Letters, Vol. 22, Núm. 3, pp. 1449-1455

  2. Modulation of KV4.3-KChIP2 Channels by IQM-266: Role of DPP6 and KCNE2

    International journal of molecular sciences, Vol. 23, Núm. 16

2021

  1. An overview of the synaptic vesicle lipid composition

    Archives of Biochemistry and Biophysics, Vol. 709

  2. Characterization of PROPPIN–Phosphoinositide Binding by Stopped-Flow Fluorescence Spectroscopy

    Methods in Molecular Biology (Humana Press Inc.), pp. 205-214

  3. Cross-linking mass spectrometry uncovers protein interactions and functional assemblies in synaptic vesicle membranes

    Nature Communications, Vol. 12, Núm. 1

  4. Dynamic Excimer (DYNEX) Imaging of Lipid Droplets

    ACS Sensors, Vol. 6, Núm. 10, pp. 3632-3639

  5. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

    Autophagy, Vol. 17, Núm. 1, pp. 1-382

2019

  1. Structural dynamics and transient lipid binding of synaptobrevin-2 tune SNARE assembly and membrane fusion

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, Núm. 18, pp. 8699-8708

2018

  1. Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex

    Nature Communications, Vol. 9, Núm. 1

2017

  1. Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease

    Nature Communications, Vol. 8, Núm. 1

  2. Structure based biophysical characterization of the PROPPIN Atg18 shows Atg18 oligomerization upon membrane binding

    Scientific Reports, Vol. 7, Núm. 1

2016

  1. PtdInsP2 and PtdSer cooperate to trap synaptotagmin-1 to the plasma membrane in the presence of calcium

    eLife, Vol. 5, Núm. OCTOBER2016

2015

  1. Characterization of PROPPIN-phosphoinositide binding and role of loop 6CD in PROPPIN-membrane binding

    Biophysical Journal, Vol. 108, Núm. 9, pp. 2223-2234

  2. Extended synaptotagmins (E-Syts): Architecture and dynamics of membrane contact sites revealed

    Proceedings of the National Academy of Sciences of the United States of America

  3. Synaptotagmin-1 binds to PIP 2 -containing membrane but not to SNAREs at physiological ionic strength

    Nature Structural and Molecular Biology, Vol. 22, Núm. 10, pp. 815-823

2014

  1. Control of membrane gaps by synaptotagmin-Ca 2+ measured with a novel membrane distance ruler

    Nature Communications, Vol. 5

  2. Phosphatidylinositol-4,5-bisphosphate enhances anionic lipid demixing by the C2 domain of PKCα

    PLoS ONE, Vol. 9, Núm. 4

2013

  1. Phosphatidylinositol 4,5-Bisphosphate Decreases the Concentration of Ca2+, Phosphatidylserine and Diacylglycerol Required for Protein Kinase C α to Reach Maximum Activity

    PLoS ONE, Vol. 8, Núm. 7

2012

  1. The membrane binding kinetics of full-length PKCα is determined by membrane lipid composition

    Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, Vol. 1821, Núm. 11, pp. 1434-1442