
FRANCISCO ANGEL
PÉREZ LARA
PROGRAMA RAMON Y CAJAL
Publications (25) FRANCISCO ANGEL PÉREZ LARA publications
2024
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Intermediate steps in the formation of neuronal SNARE complexes
Journal of Biological Chemistry, Vol. 300, Núm. 8
2023
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Intrinsic Disorder of the Neuronal SNARE Protein SNAP25a in its Pre-fusion Conformation
Journal of Molecular Biology, Vol. 435, Núm. 10
2022
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Forces, Kinetics, and Fusion Efficiency Altered by the Full-Length Synaptotagmin-1 -PI(4,5)P2Interaction in Constrained Geometries
Nano Letters, Vol. 22, Núm. 3, pp. 1449-1455
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Modulation of KV4.3-KChIP2 Channels by IQM-266: Role of DPP6 and KCNE2
International journal of molecular sciences, Vol. 23, Núm. 16
2021
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An overview of the synaptic vesicle lipid composition
Archives of Biochemistry and Biophysics, Vol. 709
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Characterization of PROPPIN–Phosphoinositide Binding by Stopped-Flow Fluorescence Spectroscopy
Methods in Molecular Biology (Humana Press Inc.), pp. 205-214
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Cross-linking mass spectrometry uncovers protein interactions and functional assemblies in synaptic vesicle membranes
Nature Communications, Vol. 12, Núm. 1
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Dynamic Excimer (DYNEX) Imaging of Lipid Droplets
ACS Sensors, Vol. 6, Núm. 10, pp. 3632-3639
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
Autophagy, Vol. 17, Núm. 1, pp. 1-382
2019
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Structural dynamics and transient lipid binding of synaptobrevin-2 tune SNARE assembly and membrane fusion
Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, Núm. 18, pp. 8699-8708
2018
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Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex
Nature Communications, Vol. 9, Núm. 1
2017
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Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease
Nature Communications, Vol. 8, Núm. 1
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Structure based biophysical characterization of the PROPPIN Atg18 shows Atg18 oligomerization upon membrane binding
Scientific Reports, Vol. 7, Núm. 1
2016
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PtdInsP2 and PtdSer cooperate to trap synaptotagmin-1 to the plasma membrane in the presence of calcium
eLife, Vol. 5, Núm. OCTOBER2016
2015
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Characterization of PROPPIN-phosphoinositide binding and role of loop 6CD in PROPPIN-membrane binding
Biophysical Journal, Vol. 108, Núm. 9, pp. 2223-2234
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Extended synaptotagmins (E-Syts): Architecture and dynamics of membrane contact sites revealed
Proceedings of the National Academy of Sciences of the United States of America
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Synaptotagmin-1 binds to PIP 2 -containing membrane but not to SNAREs at physiological ionic strength
Nature Structural and Molecular Biology, Vol. 22, Núm. 10, pp. 815-823
2014
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Control of membrane gaps by synaptotagmin-Ca 2+ measured with a novel membrane distance ruler
Nature Communications, Vol. 5
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Phosphatidylinositol-4,5-bisphosphate enhances anionic lipid demixing by the C2 domain of PKCα
PLoS ONE, Vol. 9, Núm. 4